The mission of the Biomedical Informatics Shared Resource (BISR) is to support HICCC investigators infour critical areas including: Adoption, support, and maintenance of an electronic, caBIG compliant, centralized clinical trialmanagement system; Access to key expertise in the use of advanced data analysis tools and methodologies for researchpublications and grant proposals, reflecting established best practices; Access to state-of-the-art software, databases, and models for basic and clinical research; Access to high-performance computing infrastructure for data analysis and data sharing.The BISR director and deputy director (Drs. Califano and Hripcsak) have extensive experience respectivelyin bioinformatics and clinical informatics, are active in the conduct of basic and clinical research, and havemade key contributions to Columbia's current position as a leading institution in biomedical informatics.While increasingly vital to the success of cancer research projects, biomedical informatics support is oftennot available to experimental and clinical investigators. The BISR allows HICCC investigators to tap into avast array of biomedical informatics resources at CU by providing advanced data analysis services,biomedical informatics tools and databases, and one of the largest academic computer clusters dedicatedto biological research. BISR leadership also acts as a catalyst in forging new collaborations betweenHICCC investigators and more than 40 biomedical informatics faculty at CU. Specifically, the BISRsupports the CRMO data acquisition and management requirements, works with a large team ofcaBIG/NCI funded programmers developing integrative bioinformatics platforms (geWorkbench), supportsall caBIG initiatives at CU, and is piloting the integration of pathology, clinical, and genomic data fortranslational research. Currently, a large and increasing contingent of HICCC investigators havesuccessfully used the shared resource and the BISR has been instrumental in the submission of a vastmajority of funded proposals since the last review cycle, including several R01s, large Program Projects,and a U54 for the creation of a National Center for Biomedical Computing. The projected operating budgetfor BISR is $819,068 and we are requesting $326,883.
Showing the most recent 10 out of 331 publications
