Abstract

Shared Research Resources differs from the other core facilities in the MIT CCR in that it covers a range of distributed equipment and services that broadly support the research of the CCR. This facility oversees the maintenance of infrastructure and large shared equipment essential for the research of all research groups within E17/18 as well as the CCR Facilities that benefit all CCR members. It also supports necessary safety operations and related activities. A major role of the facility is the implementation and continuance of a comprehensive Environment, Health & Safety management system being developed by MIT that encompasses safety inspections, laboratory safety and staff training. In addition, this facility provides technical support and service for both shared and laboratory equipment within the CCR.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014051-37
Application #
7668630
Study Section
Project Start
Project End
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
37
Fiscal Year
2008
Total Cost
$266,780
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Wong, Madeline Y; Chen, Kenny; Antonopoulos, Aristotelis et al. (2018) XBP1s activation can globally remodel N-glycan structure distribution patterns. Proc Natl Acad Sci U S A 115:E10089-E10098
Viswanathan, Srinivas R; Nogueira, Marina F; Buss, Colin G et al. (2018) Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. Nat Genet 50:937-943
Goods, Brittany A; Vahey, Jacqueline M; Steinschneider, Arthur F et al. (2018) Blood handling and leukocyte isolation methods impact the global transcriptome of immune cells. BMC Immunol 19:30
Kaczmarek, James C; Kauffman, Kevin J; Fenton, Owen S et al. (2018) Optimization of a Degradable Polymer-Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells. Nano Lett 18:6449-6454
Perez, Dahlia E; Henle, Andrea M; Amsterdam, Adam et al. (2018) Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology. Pigment Cell Melanoma Res 31:604-613
Wu, Connie; Li, Jiahe; Wang, Wade et al. (2018) Rationally Designed Polycationic Carriers for Potent Polymeric siRNA-Mediated Gene Silencing. ACS Nano 12:6504-6514
Ordovas-Montanes, Jose; Dwyer, Daniel F; Nyquist, Sarah K et al. (2018) Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature 560:649-654
Lam, Fred C; Morton, Stephen W; Wyckoff, Jeffrey et al. (2018) Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles. Nat Commun 9:1991
Chiu, Anthony C; Suzuki, Hiroshi I; Wu, Xuebing et al. (2018) Transcriptional Pause Sites Delineate Stable Nucleosome-Associated Premature Polyadenylation Suppressed by U1 snRNP. Mol Cell 69:648-663.e7
Weidberg, Hilla; Amon, Angelika (2018) MitoCPR-A surveillance pathway that protects mitochondria in response to protein import stress. Science 360:

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