Abstract

Shared Research Resources differs from the other core facilities in the MIT CCR in that it covers a range of distributed equipment and services that broadly support the research of the CCR. This facility oversees the maintenance of infrastructure and large shared equipment essential for the research of all research groups within E17/18 as well as the CCR Facilities that benefit all CCR members. It also supports necessary safety operations and related activities. A major role of the facility is the implementation and continuance of a comprehensive Environment, Health & Safety management system being developed by MIT that encompasses safety inspections, laboratory safety and staff training. In addition, this facility provides technical support and service for both shared and laboratory equipment within the CCR.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014051-37
Application #
7668630
Study Section
Project Start
Project End
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
37
Fiscal Year
2008
Total Cost
$266,780
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Wong, Madeline Y; Doan, Ngoc Duc; DiChiara, Andrew S et al. (2018) A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production. Biochemistry 57:2814-2827
Danai, Laura V; Babic, Ana; Rosenthal, Michael H et al. (2018) Altered exocrine function can drive adipose wasting in early pancreatic cancer. Nature 558:600-604
Dubbury, Sara J; Boutz, Paul L; Sharp, Phillip A (2018) CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature 564:141-145
Tokatlian, Talar; Kulp, Daniel W; Mutafyan, Andrew A et al. (2018) Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes. Sci Rep 8:16527
Crowell, Laura E; Lu, Amos E; Love, Kerry R et al. (2018) On-demand manufacturing of clinical-quality biopharmaceuticals. Nat Biotechnol :
Lo, Justin H; Hao, Liangliang; Muzumdar, Mandar D et al. (2018) iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer. Mol Cancer Ther 17:2377-2388
Berger, Gilles; Grauwet, Korneel; Zhang, Hong et al. (2018) Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models. Cancer Lett 416:138-148
Johnson, Hannah; White, Forest M (2018) Quantitative Analysis of Tyrosine Kinase Signaling Across Differentially Embedded Human Glioblastoma Tumors. Methods Mol Biol 1711:149-164
Phillips, Angela M; Doud, Michael B; Gonzalez, Luna O et al. (2018) Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin. Elife 7:
Parisi, Tiziana; Balsamo, Michele; Gertler, Frank et al. (2018) The Rb tumor suppressor regulates epithelial cell migration and polarity. Mol Carcinog 57:1640-1650

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