? BEHAVIORAL HEALTH AND SURVEY RESEARCH SHARED RESOURCE The purpose of the new Behavioral Health and Survey Research (BHSR) Shared Resource is to provide Duke Cancer Institute (DCI) members with evidence-based behavioral and epidemiological research methods to enable patient centered research. Behavioral and epidemiological research can serve as the bridge that helps translate science to the communities that we serve, and is thus a major priority for the DCI. BHSR investigators and staff have the extensive experience needed to help meet this need, including expertise in survey design, qualitative research, and educational materials development. Rigorous implementation of these approaches in DCI investigators? research programs will help faculty address scientific questions across cancer continuum: prevention, detection, treatment, survivorship and palliative care for both patients and their families. Since its inception with CCSG developmental funds from the DCI in 2015, and following its approval as a DCI and Duke School of Medicine Shared Resource in January 2017, the BHSR has pursued two main goals: 1) to foster communication and collaborative exchange among DCI clinical, basic, and population science investigators and 2) to promote standardization, rigor, and centralization of methods among DCI faculty. The BHSR accomplishes these goals by providing research consultation and technical support through three essential lines of service: 1) qualitative data collection and analysis, 2) survey development, and 3) educational materials development. The BHSR is committed to providing the highest quality support and has implemented strong business practices to ensure efficient and timely provision of services. With continued growth, a critical future direction for the BHSR will be to convene a BHSR Scientific Advisory Board that includes patients and family members to help guide use of research methods and growth. Since its inception in January 2015, we have provided services to 46 clients, 39 of whom were DCI members. In 2018 alone, the Behavioral Health and Survey Research shared resource provided services to 19 investigators, 14 of whom were DCI members, accounting for 75% of total usage, from 5 of the 8 DCI Research Programs. Use of this shared resource by DCI Members contributed to 17 publications over the project period.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014236-47
Application #
10118120
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-01-01
Project End
2024-12-31
Budget Start
2021-01-01
Budget End
2021-12-31
Support Year
47
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Wu, Mengxi; Huang, Po-Hsun; Zhang, Rui et al. (2018) Circulating Tumor Cell Phenotyping via High-Throughput Acoustic Separation. Small 14:e1801131
Vlahovic, Gordana; Meadows, Kellen L; Hatch, Ace J et al. (2018) A Phase I Trial of the IGF-1R Antibody Ganitumab (AMG 479) in Combination with Everolimus (RAD001) and Panitumumab in Patients with Advanced Cancer. Oncologist 23:782-790
Xu, Yinghui; Liu, Hongliang; Liu, Shun et al. (2018) Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer. Int J Cancer 143:2400-2408
Feng, Yun; Wang, Yanru; Liu, Hongliang et al. (2018) Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer. Mol Carcinog 57:216-224
Naqvi, Ibtehaj; Gunaratne, Ruwan; McDade, Jessica E et al. (2018) Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis. Mol Ther 26:1020-1031
Wen, Juyi; Liu, Hongliang; Wang, Lili et al. (2018) Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non-Small Cell Lung Cancer after Definitive Radiotherapy. J Thorac Oncol 13:660-675
Li, Bo; Wang, Yanru; Xu, Yinghui et al. (2018) Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. Int J Cancer 142:2303-2312
Gearhart-Serna, Larisa M; Jayasundara, Nishad; Tacam Jr, Moises et al. (2018) Assessing Cancer Risk Associated with Aquatic Polycyclic Aromatic Hydrocarbon Pollution Reveals Dietary Routes of Exposure and Vulnerable Populations. J Environ Public Health 2018:5610462
Bakthavatsalam, Subha; Sleeper, Mark L; Dharani, Azim et al. (2018) Leveraging ?-Glutamyl Transferase To Direct Cytotoxicity of Copper Dithiocarbamates against Prostate Cancer Cells. Angew Chem Int Ed Engl 57:12780-12784
Dai, Ziwei; Mentch, Samantha J; Gao, Xia et al. (2018) Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width. Nat Commun 9:1955

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