The University of Wisconsin Carbone Cancer Center (UWCCC) seeks continued funding for years 44-48 in pursuit of its mission to dramatically reduce the burden of cancer within and beyond its catchment. The UWCCC, which is a matrix center within the University of Wisconsin School of Medicine and Public Health (SMPH), is composed of 198 faculty members from 38 departments and 8 schools of the University of Wisconsin-Madison (UW). Our members pursue cancer care, research and education through 6 scientific programs (Human Cancer Virology, Cancer Genetic and Epigenetic Mechanisms, Tumor Microenvironment, Imaging and Radiation Sciences, Developmental Therapeutics, and Cancer Prevention and Control) supported by 10 Shared Resources. During the period 2012-2016, our members published 3324 cancer relevant manuscripts (with 66% collaborative) and were supported by $63.7M (Direct) peer-reviewed cancer relevant funding and $16.6M (Direct) non peer-reviewed funding (as of December 31, 2016). The UWCCC will accomplish this mission through nurturing a supportive cancer community, reliable infrastructure, and efficient resources. The UWCCC worked to decrease the burden of cancer in our catchment and beyond through prioritized research areas (e.g. innovative therapies and biomarkers, cancer imaging and expanded population-based cancer research), enhanced research platforms (e.g. improved clinical research infrastructure and shared resources), increased efforts to build mission-related philanthropy and expanded local to global partnerships.

Public Health Relevance

The University of Wisconsin Carbone Cancer Center (UWCCC), which is a matrix center within the University of Wisconsin School of Medicine and Public Health (SMPH), seeks to dramatically reduce the burden of cancer within and beyond our catchment. Specifically, the UWCCC will do this by decreasing cancer incidence and mortality among populations within our catchment area and beyond, including our minority and underserved populations. We will facilitate pursuit of this goal through partnerships with other health delivery systems and state and community agencies for dissemination of evidence-based findings. The UWCCC will accomplish the aforementioned goals through nurturing a supportive cancer community, reliable infrastructure and efficient resources. The UWCCC has started to decrease the burden of cancer in our catchment and beyond through prioritized research areas (e.g. innovative therapies and biomarkers, cancer imaging and expanded population- based cancer research), enhanced research platforms (e.g. improved clinical research infrastructure and shared resources), increased efforts to build mission-related philanthropy and expanded local to global partnerships.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014520-46
Application #
9922999
Study Section
Subcommittee I - Transistion to Independence (NCI)
Program Officer
Shafik, Hasnaa
Project Start
1997-04-25
Project End
2023-03-31
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
46
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Hart, Vicki; Trentham-Dietz, Amy; Berkman, Amy et al. (2018) The association between post-diagnosis health behaviors and long-term quality of life in survivors of ductal carcinoma in situ: a population-based longitudinal cohort study. Qual Life Res 27:1237-1247
Lee, Hye Jin; Ehlerding, Emily B; Cai, Weibo (2018) Antibody-Based Tracers for PET/SPECT Imaging of Chronic Inflammatory Diseases. Chembiochem :
Elsaid, Mohamed Y; Shahi, Ankita; Wang, Albert R et al. (2018) Enhanced Radiosensitivity in Solid Tumors using a Tumor-selective Alkyl Phospholipid Ether Analog. Mol Cancer Ther 17:2320-2328
Dennison, Kirsten L; Chack, Aaron C; Hickman, Maureen Peters et al. (2018) Ept7, a quantitative trait locus that controls estrogen-induced pituitary lactotroph hyperplasia in rat, is orthologous to a locus in humans that has been associated with numerous cancer types and common diseases. PLoS One 13:e0204727
Zaitoun, Ismail S; Cikla, Ulas; Zafer, Dila et al. (2018) Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy. Sci Rep 8:9166
Liu, Zhen; Ehlerding, Emily B; Cai, Weibo et al. (2018) One-step synthesis of an 18F-labeled boron-derived methionine analog: a substitute for 11C-methionine? Eur J Nucl Med Mol Imaging 45:582-584
Chakravarty, Rubel; Siamof, Cerise M; Dash, Ashutosh et al. (2018) Targeted ?-therapy of prostate cancer using radiolabeled PSMA inhibitors: a game changer in nuclear medicine. Am J Nucl Med Mol Imaging 8:247-267
Albertini, Mark R; Yang, Richard K; Ranheim, Erik A et al. (2018) Pilot trial of the hu14.18-IL2 immunocytokine in patients with completely resectable recurrent stage III or stage IV melanoma. Cancer Immunol Immunother 67:1647-1658
Saghiri, Mohammad Ali; Asatourian, Armen; Nguyen, Eric H et al. (2018) Hydrogel Arrays and Choroidal Neovascularization Models for Evaluation of Angiogenic Activity of Vital Pulp Therapy Biomaterials. J Endod 44:773-779
Jamali, Nasim; Sorenson, Christine M; Sheibani, Nader (2018) Vitamin D and regulation of vascular cell function. Am J Physiol Heart Circ Physiol 314:H753-H765

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