The Prevention Center Shared Resource (PCSR) functions as a staffed, full-service research facility and provides a physical space for research staff to perform Consortium clinical and epidemiologic studies. Resource staff encourages interdisciplinary, collaborative research within the Consortium by directing faculty to consult with other members who have used the shared resource and who might bring added scientific dimension and perspective to their research. The PCSR also provides training and certification for technical staff, and serves as a support resource and training facility for investigators, fellows and students. The PCSR supports this research by offering the services of three important and distinct intervention-focused facilities. The Research Clinic (RC) provides space, equipment and personnel to support the conduct of quality biologic research studies. Services provided include physical exams, gynecologic exams, collection of vital signs and anthropometric measurements, collection of biospecimens, quick turn-around specimen processing and short- term specimen storage and biospecimen tracking. RC staffs are also trained to perform minimally invasive procedures, including RPFNA (random periaereolar fine needle aspiration) of the breast and abdominal fat biopsies. The Exercise Research Center (ERC) is a state-of-the-art resource that enables Consortium investigators to conduct studies in physical activity intervention research. The resource provides services to investigators at a lower cost than outside facilities, and also provides oversight for supervised exercise sessions, and research data collection, while maintaining privacy and convenient access to study participants. The ERC conducts exercise training, exercise testing that includes V02 max, submaximal exercise tolerance testing, spirometry, strength and flexibility assessment, and indirect calorimetry (REE) testing. Trained exercise physiologists are available to create tailored exercise programs for study participants and to oversee exercise sessions. The Human Nutrition Laboratory (HNL) provides comprehensive support for the conduct of human feeding studies as well as the food component of behavioral and community nutrition intervention studies. Services provided include study diet design, food production and delivery, meal service, data collection, and study participant management and monitoring according to diet intake protocols. The HNL also provides nutritional support for participants in exercise or research intervention studies conducted in other components of the PCSR.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA015704-43
Application #
9406715
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-01-01
Budget End
2018-12-31
Support Year
43
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
Briant, Katherine J; Sanchez, Janeth I; Ibarra, Genoveva et al. (2018) Using a Culturally Tailored Intervention to Increase Colorectal Cancer Knowledge and Screening among Hispanics in a Rural Community. Cancer Epidemiol Biomarkers Prev 27:1283-1288
Xu, Chang; Nikolova, Olga; Basom, Ryan S et al. (2018) Functional Precision Medicine Identifies Novel Druggable Targets and Therapeutic Options in Head and Neck Cancer. Clin Cancer Res 24:2828-2843
Miller, Chris P; Tsuchida, Connor; Zheng, Ying et al. (2018) A 3D Human Renal Cell Carcinoma-on-a-Chip for the Study of Tumor Angiogenesis. Neoplasia 20:610-620
Baker, K Scott; Syrjala, Karen L (2018) Long-term complications in adolescent and young adult leukemia survivors. Hematology Am Soc Hematol Educ Program 2018:146-153
Gavvovidis, Ioannis; Leisegang, Matthias; Willimsky, Gerald et al. (2018) Targeting Merkel Cell Carcinoma by Engineered T Cells Specific to T-Antigens of Merkel Cell Polyomavirus. Clin Cancer Res 24:3644-3655
Paulson, K G; Voillet, V; McAfee, M S et al. (2018) Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA. Nat Commun 9:3868
Puronen, Camille E; Cassaday, Ryan D; Stevenson, Philip A et al. (2018) Long-Term Follow-Up of 90Y-Ibritumomab Tiuxetan, Fludarabine, and Total Body Irradiation-Based Nonmyeloablative Allogeneic Transplant Conditioning for Persistent High-Risk B Cell Lymphoma. Biol Blood Marrow Transplant 24:2211-2215
Witzky, Anne; Hummels, Katherine R; Tollerson 2nd, Rodney et al. (2018) EF-P Posttranslational Modification Has Variable Impact on Polyproline Translation in Bacillus subtilis. MBio 9:
Rosenthal, Elisabeth A; Shirts, Brian H; Amendola, Laura M et al. (2018) Rare loss of function variants in candidate genes and risk of colorectal cancer. Hum Genet 137:795-806
Verboon, Jeffrey M; Decker, Jacob R; Nakamura, Mitsutoshi et al. (2018) Correction: Wash exhibits context-dependent phenotypes and, along with the WASH regulatory complex, regulates Drosophila oogenesis (doi:10.1242/211573). J Cell Sci 131:

Showing the most recent 10 out of 1267 publications