The 3 new senior leaders, Dr. Gudkov, Dr. Adjei, and Mr. Walker, bring fresh ideas and perspectives to theInstitute as well as a wealth of scientific program development, and administrative leadership experiencegarnered from their involvement at other major NCI-designated cancer programs (Case ComprehensiveCancer Center, Mayo Clinic Cancer Center and the Ohio State University Comprehensive Cancer Center,respectively).Each of the Senior Leaders also plays a pivotal role in a CCSG Programs or Shared Resources. Dr. Adjeiserves as Leader of the Molecular Targets and Experimental Therapeutics (MTET) and oversees ClinicalResearch Services, Dr. Gudkov is Leader of the Cell Stress and Biophysical Therapies (CSBT) Program, andDr. James Marshall leads the Cancer Prevention and Population Sciences (CPPS) program. Dr. CandaceJohnson is an active participant in the Prostate Program and MTET, while Dr. Trump participates in theMolecular Targets and Experimental Therapeutics Program. Mr. Walker serves as the CCSG Administratorand oversees the CCSG shared resources. All members of the Senior Leadership Team are active in thefaculty recruitment process, serving as chairs or members of search committees. Further they are alsoinvolved in coordinating the EAB meetings, annual retreats, symposia/seminar series and participating indevelopment activities. Each of these leaders is also active in national cancer research forums and wellintegrated into leadership and committee positions in these external arenas (ASCO, AACR, AACI, NCCN, NCI[caBIG, IRGs, parent committees]) assuring their awareness of and participation in deliberations regardingimportant national topics in cancer research, care and education and guaranteeing RPCI awareness of andleadership in the national trends.The Senior Leadership team interacts informally on a daily basis and meets formally on a weekly basis in theprimary administrative leadership forum known as the RPCI Executive Council. Chaired by Dr. Trump, theExecutive Council is the major decision-making body of the Institute, responsible for the on-going oversight ofthe RPCI and addressing all functional issues raised by its members. In addition, the Senior Leadershipparticipates on the CCSG Steering Committee, a committee that meets monthly and includes the researchprogram leaders as well as leaders of important CCSG and Institute initiatives [e.g., Imaging Development,Health Disparities]. The CCSG Steering Committee, chaired by Dr. Trump, provides a venue for strategicplanning, program evaluation, membership review and approval and review of existing and proposed sharedresources. Although there are several other venues where the Senior Leadership participates, it is throughthese two committees that primary decision-making is accomplished.There has been dramatic growth in RPCI during the last funding cycle. Over this funding cycle (2002 to 2006)the Senior Leadership team worked together to recruit more than 100 cancer investigators and clinicians,increase NCI funding by 74%, increase accruals to therapeutic investigator-initiated clinical trials and increasein out patient volume by 42% over this time period. As the number of cancer-focused basic, translational,clinical and population investigators at the RPCI have grown, four new Shared Resources have beenestablished to support the needs of the membership with three more now in development. It is anticipated thatthe current Senior Leadership team will continue this successful trajectory via developing and executing longtermvision and strategic planning for the Institute.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016056-32
Application #
7714406
Study Section
Subcommittee G - Education (NCI)
Project Start
2008-07-28
Project End
2013-04-30
Budget Start
2008-07-28
Budget End
2009-04-30
Support Year
32
Fiscal Year
2008
Total Cost
$123,134
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
824771034
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Eng, Diana G; Kaverina, Natalya V; Schneider, Remington R S et al. (2018) Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing. Kidney Int 93:1240-1246
Ling, Xiang; Wu, Wenjie; Fan, Chuandong et al. (2018) An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer. J Exp Clin Cancer Res 37:240
Chung, Sejin; Vail, Paris J; Witkiewicz, Agnieszka K et al. (2018) Coordinately targeting cell cycle checkpoint functions in integrated models of pancreatic cancer. Clin Cancer Res :
Mohammadpour, Hemn; O'Neil, Rachel; Qiu, Jingxin et al. (2018) Blockade of Host ?2-Adrenergic Receptor Enhances Graft-versus-Tumor Effect through Modulating APCs. J Immunol 200:2479-2488
Hsu, Alice H; Lum, Michelle A; Shim, Kang-Sup et al. (2018) Crosstalk between PKC? and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium. Cell Rep 24:655-669
Sandlesh, Poorva; Juang, Thierry; Safina, Alfiya et al. (2018) Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene. PLoS One 13:e0199785
Zhang, Dingxiao; Zhao, Shuhong; Li, Xinyun et al. (2018) Prostate Luminal Progenitor Cells in Development and Cancer. Trends Cancer 4:769-783
Hong, Chi-Chen; Sucheston-Campbell, Lara E; Liu, Song et al. (2018) Genetic Variants in Immune-Related Pathways and Breast Cancer Risk in African American Women in the AMBER Consortium. Cancer Epidemiol Biomarkers Prev 27:321-330
Damayanti, Nur P; Budka, Justin A; Khella, Heba W Z et al. (2018) Therapeutic Targeting of TFE3/IRS-1/PI3K/mTOR Axis in Translocation Renal Cell Carcinoma. Clin Cancer Res 24:5977-5989
Mayor, Paul; Starbuck, Kristen; Zsiros, Emese (2018) Adoptive cell transfer using autologous tumor infiltrating lymphocytes in gynecologic malignancies. Gynecol Oncol 150:361-369

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