Abstract

The mission of the MCV/VCU Cancer Center is to coordinate the cancer research, patient-care services, oncology education and community outreach cancer programs at our institution. The center is organized with nine program areas, each with a coordinator. The research program areas include Cancer Cell Biology, Tumor Immunology, Pharmacology of Anti-Cancer Drugs, Carcinogenesis and Clinical Cancer Research. The non-research program areas include Cancer Training and Education, Clinical Cancer Services and Rehabilitation, Detection and Screening and Community Interaction. In addition, the Center has developed an Epi-Stat Unit, Tumor Registry, Cell Analysis and Sorting Lab, Tumor Immunobiology Lab, Media Preparation Lab, Histopathology Lab, Clinical Cancer Research Core and Evaluation components. In addition to these shared resources and program areas, the Core Support Grant provides some developmental funds for new projects and programs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016059-10
Application #
3101530
Study Section
Cancer Center Support Grant Review Committee (CCS)
Project Start
1978-12-01
Project End
1987-11-30
Budget Start
1984-12-01
Budget End
1985-11-30
Support Year
10
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Type
Overall Medical
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Warthan, Michelle D; Washington, Sonya L; Franzese, Samone E et al. (2018) The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma. Biol Reprod 98:309-322
Booth, Laurence; Roberts, Jane L; Rais, Rumeesa et al. (2018) [Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration. Oncotarget 9:6062-6074
Floros, Konstantinos V; Lochmann, Timothy L; Hu, Bin et al. (2018) Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy. Proc Natl Acad Sci U S A 115:E2594-E2603
Brabec, Viktor; Kasparkova, Jana; Menon, Vijay et al. (2018) Polynuclear Platinum Complexes. Structural Diversity and DNA Binding. Met Ions Life Sci 18:
Lv, Dong-Wen; Zhang, Kun; Li, Renfeng (2018) Interferon regulatory factor 8 regulates caspase-1 expression to facilitate Epstein-Barr virus reactivation in response to B cell receptor stimulation and chemical induction. PLoS Pathog 14:e1006868
Rizzo, Juliana; Colombo, Ana C; Zamith-Miranda, Daniel et al. (2018) The putative flippase Apt1 is required for intracellular membrane architecture and biosynthesis of polysaccharide and lipids in Cryptococcus neoformans. Biochim Biophys Acta Mol Cell Res 1865:532-541
Talukdar, Sarmistha; Pradhan, Anjan K; Bhoopathi, Praveen et al. (2018) MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. Proc Natl Acad Sci U S A 115:5768-5773
Liu, Runping; Li, Xiaojiaoyang; Huang, Zhiming et al. (2018) C/EBP homologous protein-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury in mice. Hepatology 67:1441-1457
Moro, Kazuki; Kawaguchi, Tsutomu; Tsuchida, Junko et al. (2018) Ceramide species are elevated in human breast cancer and are associated with less aggressiveness. Oncotarget 9:19874-19890
El-Rami, Fadi; Kong, Xiangzhen; Parikh, Hardik et al. (2018) Analysis of essential gene dynamics under antibiotic stress in Streptococcus sanguinis. Microbiology 164:173-185

Showing the most recent 10 out of 586 publications