Abstract

The Molecular Biology Shared Resource of the MCC has been in operation since April 1990, offering Cancer Center members access to basic molecular genetic techniques, including plasmid, bacteriophage and insert DNA production. In addition to this basic service, the Molecular Biology Shared Resource offers customized subcloning services, library screening and protein expression on an as-needed basis to Massey Cancer Center investigators. A Molecular Dynamics PhosphoImager is available for radioisotopic detection, imaging, quantitation, and densitometric scanning. One full-time senior research specialist and a full-time junior research specialist staff the facility. User fees cover part of the operating costs of the facility.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016059-23
Application #
6592798
Study Section
Project Start
2002-05-16
Project End
2007-04-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
23
Fiscal Year
2002
Total Cost
$41,211
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Type
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Booth, Laurence; Roberts, Jane L; Rais, Rumeesa et al. (2018) [Neratinib + Valproate] exposure permanently reduces ERBB1 and RAS expression in 4T1 mammary tumors and enhances M1 macrophage infiltration. Oncotarget 9:6062-6074
Floros, Konstantinos V; Lochmann, Timothy L; Hu, Bin et al. (2018) Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy. Proc Natl Acad Sci U S A 115:E2594-E2603
Warthan, Michelle D; Washington, Sonya L; Franzese, Samone E et al. (2018) The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma. Biol Reprod 98:309-322
Lv, Dong-Wen; Zhang, Kun; Li, Renfeng (2018) Interferon regulatory factor 8 regulates caspase-1 expression to facilitate Epstein-Barr virus reactivation in response to B cell receptor stimulation and chemical induction. PLoS Pathog 14:e1006868
Rizzo, Juliana; Colombo, Ana C; Zamith-Miranda, Daniel et al. (2018) The putative flippase Apt1 is required for intracellular membrane architecture and biosynthesis of polysaccharide and lipids in Cryptococcus neoformans. Biochim Biophys Acta Mol Cell Res 1865:532-541
Brabec, Viktor; Kasparkova, Jana; Menon, Vijay et al. (2018) Polynuclear Platinum Complexes. Structural Diversity and DNA Binding. Met Ions Life Sci 18:
Liu, Runping; Li, Xiaojiaoyang; Huang, Zhiming et al. (2018) C/EBP homologous protein-induced loss of intestinal epithelial stemness contributes to bile duct ligation-induced cholestatic liver injury in mice. Hepatology 67:1441-1457
Moro, Kazuki; Kawaguchi, Tsutomu; Tsuchida, Junko et al. (2018) Ceramide species are elevated in human breast cancer and are associated with less aggressiveness. Oncotarget 9:19874-19890
Talukdar, Sarmistha; Pradhan, Anjan K; Bhoopathi, Praveen et al. (2018) MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. Proc Natl Acad Sci U S A 115:5768-5773
Luzi, Nicole M; Lyons, Charles E; Peterson, Darrell L et al. (2018) Kinetics and inhibition studies of the L205R mutant of cAMP-dependent protein kinase involved in Cushing's syndrome. FEBS Open Bio 8:606-613

Showing the most recent 10 out of 586 publications