The Massey Cancer Center is an administrative matrix center at Virginia Commonwealth University whose mission is to provide comprehensive cancer services in the areas of basic, clinical, and population research, outreach, and education to the State of Virginia and the nation. The major goals of the Center are 1) to facilitate high-quality basic, clinical, and population-based research focused on the cancer problem and 2) to promote interdisciplinary collaborations among the scientific programs and members of the Center, in order to generate more effective interventions for cancer prevention and treatment. Research activities of the Massey Cancer Center are carried out through five established research programs which are Developmental Therapeutics, Cancer Cell Biology, Immune Mechanisms, Cancer Control, and Radiation Biology and Oncology. The programs are structured to include both basic research and either clinical translational or applied population research so as to facilitate rapid implementation of research findings in the treatment and prevention of cancer. In order to provide support for the predominantly peer-reviewed research base of the Massey Cancer Center programs, several shared resources are operated by the Center including those in Clinical Research, Biostatistics, Flow Cytometry, Hybridoma/Cell Production, Molecular Biology, Nucleic Acid Sequencing and Synthesis, Structural Biology, and Transgenic Mouse. This application requests Cancer Center Support Grant continuation to support these shared resources as well as senior leadership, program leadership, administration, protocol-specific research, planning and evaluation, protocol review and monitoring, and developmental funding which are necessary to facilitate and stimulate interdisciplinary cancer research through the scientific programs of the Center.
| Kazarian, Elizabeth; Son, HyunYoung; Sapao, Paulene et al. (2018) SPAG17 Is Required for Male Germ Cell Differentiation and Fertility. Int J Mol Sci 19: |
| Farrell, Nicholas P; Gorle, Anil K; Peterson, Erica J et al. (2018) Metalloglycomics. Met Ions Life Sci 18: |
| Ordoñez, José A; Bandyopadhyay, Dipankar; Lachos, Victor H et al. (2018) Geostatistical estimation and prediction for censored responses. Spat Stat 23:109-123 |
| Abeyawardhane, Dinendra L; Fernández, Ricardo D; Murgas, Cody J et al. (2018) Iron Redox Chemistry Promotes Antiparallel Oligomerization of ?-Synuclein. J Am Chem Soc 140:5028-5032 |
| Zhang, Yong; Liu, Hong; Li, Wei et al. (2018) Intraflagellar transporter protein 140 (IFT140), a component of IFT-A complex, is essential for male fertility and spermiogenesis in mice. Cytoskeleton (Hoboken) 75:70-84 |
| Singh, Dhirendra P; Kaur, Gagandeep; Bagam, Prathyusha et al. (2018) Membrane microdomains regulate NLRP10- and NLRP12-dependent signalling in A549 cells challenged with cigarette smoke extract. Arch Toxicol 92:1767-1783 |
| Lochmann, Timothy L; Floros, Konstantinos V; Naseri, Mitra et al. (2018) Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression. Clin Cancer Res 24:360-369 |
| Zhou, Liang; Zhang, Yu; Sampath, Deepak et al. (2018) Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo. Br J Cancer 118:388-397 |
| Huang, Dian; Leslie, Kevin A; Guest, Daniel et al. (2018) High-Speed Live-Cell Interferometry: A New Method for Quantifying Tumor Drug Resistance and Heterogeneity. Anal Chem 90:3299-3306 |
| Salman, Ali; Koparde, Vishal; Hall, Charles E et al. (2018) Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation. Front Immunol 9:2284 |
Showing the most recent 10 out of 586 publications
