Abstract

As a Research Staff Investigator, Dr Steven Grossman will bridge the Cancer Molecular Genetics (CMG) and Developmental Therapeutics (DT) programs together, through his preclinical and research interests and his membership in both programs. His laboratory research in p53 biology, and clinical and translational research in gastrointestinal cancer, will be focal points around which additional collaborative and translational research is expected to grow. Dr Grossman will play a special role in bringing together multiple basic scientists, prevention and control researchers, and translational-clinical investigators in gastrointestinal cancer at the Center to develop a highly interactive translation focus in that high priority area.

Public Health Relevance

In his position as a Research Staff Investigator. Dr Steven Grossman contribute to the public health by expanding the knowledge base of p53 biology and translating this information into clinical trials for the treatment of gastrointestinal cancer.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016059-31
Application #
8299699
Study Section
Subcommittee G - Education (NCI)
Project Start
1978-12-01
Project End
2017-04-30
Budget Start
2012-08-30
Budget End
2013-04-30
Support Year
31
Fiscal Year
2012
Total Cost
$36,850
Indirect Cost
$12,606

  Institution

Name
Virginia Commonwealth University
Department
Type
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Huang, Dian; Leslie, Kevin A; Guest, Daniel et al. (2018) High-Speed Live-Cell Interferometry: A New Method for Quantifying Tumor Drug Resistance and Heterogeneity. Anal Chem 90:3299-3306
Salman, Ali; Koparde, Vishal; Hall, Charles E et al. (2018) Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation. Front Immunol 9:2284
Maczis, Melissa A; Maceyka, Michael; Waters, Michael R et al. (2018) Sphingosine kinase 1 activation by estrogen receptor ?36 contributes to tamoxifen resistance in breast cancer. J Lipid Res 59:2297-2307
Deng, Yongqiang; Pakdel, Mehrshad; Blank, Birgit et al. (2018) Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network. Dev Cell 47:464-478.e8
Nulton, Tara J; Kim, Nak-Kyeong; DiNardo, Laurence J et al. (2018) Patients with integrated HPV16 in head and neck cancer show poor survival. Oral Oncol 80:52-55
Porter-Stransky, Kirsten A; Centanni, Samuel W; Karne, Saumya L et al. (2018) Noradrenergic Transmission at Alpha1-Adrenergic Receptors in the Ventral Periaqueductal Gray Modulates Arousal. Biol Psychiatry :
Cobb, Caroline O; Soule, Eric K; Rudy, Alyssa K et al. (2018) Patterns and Correlates of Tobacco and Cannabis co-use by Tobacco Product Type: Findings from the Virginia Youth Survey. Subst Use Misuse 53:2310-2319
Sonnenschein, Halie A; Lawrence, Kenneth F; Wittenberg, Karli A et al. (2018) Suppressor of IKKepsilon forms direct interactions with cytoskeletal proteins, tubulin and ?-actinin, linking innate immunity to the cytoskeleton. FEBS Open Bio 8:1064-1082
Curry, Zachary A; Wilkerson, Jenny L; Bagdas, Deniz et al. (2018) Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy. J Pharmacol Exp Ther 366:169-183
Radwa?ska, Malwina J; Jaskó?owski, Mateusz; Davydova, Elena et al. (2018) The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol 74:681-689

Showing the most recent 10 out of 586 publications