Abstract

The Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) places a high priority on translating the research that arises from each of its programs into pilot and Phase I clinical trials. Recent positive actions to formalize and accelerate translation of pre-clinical science have resulted in an increase in the number of early phase clinical investigator-initiated clinical trials developed at MCC. Support for these trials is available through three Clinical Research Nurses and two Data Managers, each of whom has experience in early phase trials. Solicited concepts from the MCC membership are prioritized by a committee composed of senior leaders and clinical trial experts. Concepts identified by this process are considered

Public Health Relevance

The performance of high quality pilot and Phase I clinical trials requires a strong study team including Clinical Research Nurses and Data Managers. The Protocol Specific Research Support component of the CCSG supports three experienced Research Nurses and two Data Managers who are dedicated to Phase I and II cancer clinical trials.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016059-32
Application #
8559591
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
32
Fiscal Year
2013
Total Cost
$35,239
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Type
DUNS #
105300446
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

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Cobb, Caroline O; Soule, Eric K; Rudy, Alyssa K et al. (2018) Patterns and Correlates of Tobacco and Cannabis co-use by Tobacco Product Type: Findings from the Virginia Youth Survey. Subst Use Misuse 53:2310-2319
Sonnenschein, Halie A; Lawrence, Kenneth F; Wittenberg, Karli A et al. (2018) Suppressor of IKKepsilon forms direct interactions with cytoskeletal proteins, tubulin and ?-actinin, linking innate immunity to the cytoskeleton. FEBS Open Bio 8:1064-1082
Curry, Zachary A; Wilkerson, Jenny L; Bagdas, Deniz et al. (2018) Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy. J Pharmacol Exp Ther 366:169-183
Radwa?ska, Malwina J; Jaskó?owski, Mateusz; Davydova, Elena et al. (2018) The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol 74:681-689
Ginder, Gordon D; Williams Jr, David C (2018) Readers of DNA methylation, the MBD family as potential therapeutic targets. Pharmacol Ther 184:98-111
Lancina 3rd, Michael G; Wang, Juan; Williamson, Geoffrey S et al. (2018) DenTimol as A Dendrimeric Timolol Analogue for Glaucoma Therapy: Synthesis and Preliminary Efficacy and Safety Assessment. Mol Pharm 15:2883-2889
Vascak, Michal; Jin, Xiaotao; Jacobs, Kimberle M et al. (2018) Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury. Cereb Cortex 28:1625-1644
Chernoukhov, A; Hussein, A; Nkurunziza, S et al. (2018) Bayesian inference in time-varying additive hazards models with applications to disease mapping. Environmetrics 29:

Showing the most recent 10 out of 586 publications