Abstract

The New York University Cancer Center represents an interdisciplinary and interdepartmental program designed to coordinate and interrelate the various basic and clinical cancer research programs in the Institutions, to develop resources in the appropriate laboratories and clinics, to foster optimal and up-to-date education in oncology, and to implement multidiscplinary and therapeutic modalities. The objectives of the Cancer Center Core grant are to support this interdepartmental structure, to develop and maintain core units, constituted by instrumentation units, animal colony facilities, laboratory of oncopharmacology, coordinate tumor registry and an epi/stat unit, and to support the establishment of multiple oncology programs through the formation of a patient research unit and clinical investigation laboratories. Thus, in conjunction with individual grants and program grants, individual funds, and additional private sources of support, the Core grant is being used to support a strong coherent and broadly based oncological program.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-11
Application #
3101565
Study Section
Cancer Center Support Grant Review Committee (CCS)
Project Start
1975-06-30
Project End
1989-04-30
Budget Start
1987-12-01
Budget End
1989-04-30
Support Year
11
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Type
Overall Medical
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012

  Publications

Saint Fleur-Lominy, Shella; Maus, Mate; Vaeth, Martin et al. (2018) STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia. Cell Rep 24:3045-3060.e5
Puranik, Amrutesh S; Leaf, Irina A; Jensen, Mark A et al. (2018) Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney. Sci Rep 8:13948
Cui, Xin; Morales, Renee-Tyler Tan; Qian, Weiyi et al. (2018) Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis. Biomaterials 161:164-178
Weng, Mao-Wen; Lee, Hyun-Wook; Park, Sung-Hyun et al. (2018) Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis. Proc Natl Acad Sci U S A 115:E6152-E6161
Burgess, Hannah M; Pourchet, Aldo; Hajdu, Cristina H et al. (2018) Targeting Poxvirus Decapping Enzymes and mRNA Decay to Generate an Effective Oncolytic Virus. Mol Ther Oncolytics 8:71-81
Wong, Serre-Yu; Coffre, Maryaline; Ramanan, Deepshika et al. (2018) B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains. J Immunol 201:1442-1451
Handler, Jesse; Cullis, Jane; Avanzi, Antonina et al. (2018) Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-? exposure. Oncogene 37:4334-4342
Diamond, Julie M; Vanpouille-Box, Claire; Spada, Sheila et al. (2018) Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs. Cancer Immunol Res 6:910-920
Fan, Xiaozhou; Peters, Brandilyn A; Jacobs, Eric J et al. (2018) Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults. Microbiome 6:59
Chen, Danqi; Fang, Lei; Mei, Shenglin et al. (2018) Erratum: ""Regulation of Chromatin Assembly and Cell Transformation by Formaldehyde Exposure in Human Cells"". Environ Health Perspect 126:019001

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