Abstract

The NYU Kaplan Comprehensive Cancer Center is an interdisciplinary and interdepartmental program designed to foster, enhance and coordinate the conduct of oncology research, education and patient care activity at NYU Medical Center. Gaining comprehensive status in 1991 and merging with the cancer center of the Institute of Environmental Medicine in 1992, the Center now represents the total spectrum of the institution's cancer activities. Its membership consists of NYU medical school faculty actively engaged in cancer research at all levels of investigation. The Center promotes through its program orientation and specialized shared resource units, the collaboration and technology transfer intended to more rapidly translate the benefits of research into more effective approaches to cancer. A broad range of oncology research is being conducted at the Center through nine program units and the support of seventeen shared resources. The Center places particular emphasis on elucidating the molecular and genetic events responsible for cellular transformation; the host defense mechanisms which regulate the immune response; the etiologic agents within the environment which cause or contribute to cancer; and the therapies and prevention which will prove to be more effective.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-20
Application #
2007185
Study Section
Cancer Center Support Review Committee (CCS)
Program Officer
Mccormick, Patricia
Project Start
1975-06-30
Project End
1998-11-30
Budget Start
1996-12-01
Budget End
1998-11-30
Support Year
20
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Evensen, Nikki A; Madhusoodhan, P Pallavi; Meyer, Julia et al. (2018) MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia. Haematologica 103:830-839
Lee, Hyun-Wook; Park, Sung-Hyun; Weng, Mao-Wen et al. (2018) E-cigarette smoke damages DNA and reduces repair activity in mouse lung, heart, and bladder as well as in human lung and bladder cells. Proc Natl Acad Sci U S A 115:E1560-E1569
Sun, Qi; Rabbani, Piul; Takeo, Makoto et al. (2018) Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. J Invest Dermatol 138:1591-1600
Formenti, Silvia C; Rudqvist, Nils-Petter; Golden, Encouse et al. (2018) Radiotherapy induces responses of lung cancer to CTLA-4 blockade. Nat Med 24:1845-1851
Xu, Yang; Taylor, Paul; Andrade, Joshua et al. (2018) Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma. Cancer Res 78:6539-6548
Gagner, Jean-Pierre; Zagzag, David (2018) Probing Glioblastoma Tissue Heterogeneity with Laser Capture Microdissection. Methods Mol Biol 1741:209-220
Tsay, Jun-Chieh J; Wu, Benjamin G; Badri, Michelle H et al. (2018) Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer. Am J Respir Crit Care Med 198:1188-1198
Martin, Patricia K; Marchiando, Amanda; Xu, Ruliang et al. (2018) Autophagy proteins suppress protective type I interferon signalling in response to the murine gut microbiota. Nat Microbiol 3:1131-1141
de la Parra, Columba; Ernlund, Amanda; Alard, Amandine et al. (2018) A widespread alternate form of cap-dependent mRNA translation initiation. Nat Commun 9:3068
Coux, Rémi-Xavier; Teixeira, Felipe Karam; Lehmann, Ruth (2018) L(3)mbt and the LINT complex safeguard cellular identity in the Drosophila ovary. Development 145:

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