The Kaplan Comprehensive Cancer Center (KCCC) is the organization unit of NYU Medical Medical Center bringing together basic, epidemiologic, and clinical scientists to further the progress against cancer. Created in 1975, and now in its 23rd year of uninterrupted NCI core grant funding, the Center seeks five additional years of support. Recent changes in leadership have engendered the strengthening of the Center's programmatic structure, shared resource units and overall commitment by NYU Medical Center. Renewed institutional support to the KCCC is manifested in additional research and clinical space, and financial and organization status comparable to other academic departments; in addition, the new director, Franco M. Muggia, M.D., holds a concomitant appointment as Associate Dean of the medical school. Since assuming the director's position on July 1, 1997, Dr. Muggia has promoted a further integration of clinical and laboratory investigators within the outstanding basic science programs and has sought to strengthen translational research in environmental carcinogenesis and population science, based at the Nelson Institute of Environmental Medicine-a unique feature of this cancer center. Future plans embrace the vision of greater organ-oriented research through new programs in Breast and Genitourinary Cancer Research; another such study, Neuro-oncology, is presented as a developing program. Further reflecting the cross-fertilization of scientific disciplines, two new shared resources have been created: Population Genetics and Molecular Diagnostics. Blending the Center's overall expansion with selected organizational consolidation, we envision continued significant accomplishment through the 9 programs and 13 shared resources which foster and facilitate interchange among its 187 members. Their productivity promises to be reflected in cancer prevention and treatment efforts within the population we serve, and in research advances felt nationally and internationally.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-22
Application #
6124417
Study Section
Subcommittee G - Education (NCI)
Program Officer
Silkensen, Shannon M
Project Start
1975-06-30
Project End
2003-02-28
Budget Start
2000-05-19
Budget End
2003-02-28
Support Year
22
Fiscal Year
2000
Total Cost
$1,475,754
Indirect Cost
Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Xu, Yang; Taylor, Paul; Andrade, Joshua et al. (2018) Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma. Cancer Res 78:6539-6548
Gagner, Jean-Pierre; Zagzag, David (2018) Probing Glioblastoma Tissue Heterogeneity with Laser Capture Microdissection. Methods Mol Biol 1741:209-220
Tsay, Jun-Chieh J; Wu, Benjamin G; Badri, Michelle H et al. (2018) Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer. Am J Respir Crit Care Med 198:1188-1198
Martin, Patricia K; Marchiando, Amanda; Xu, Ruliang et al. (2018) Autophagy proteins suppress protective type I interferon signalling in response to the murine gut microbiota. Nat Microbiol 3:1131-1141
Coux, Rémi-Xavier; Teixeira, Felipe Karam; Lehmann, Ruth (2018) L(3)mbt and the LINT complex safeguard cellular identity in the Drosophila ovary. Development 145:
de la Parra, Columba; Ernlund, Amanda; Alard, Amandine et al. (2018) A widespread alternate form of cap-dependent mRNA translation initiation. Nat Commun 9:3068
Fanok, Melania H; Sun, Amy; Fogli, Laura K et al. (2018) Role of Dysregulated Cytokine Signaling and Bacterial Triggers in the Pathogenesis of Cutaneous T-Cell Lymphoma. J Invest Dermatol 138:1116-1125
Patibandla, Jay R; Fehniger, Julia E; Levine, Douglas A et al. (2018) Small cell cancers of the female genital tract: Molecular and clinical aspects. Gynecol Oncol 149:420-427
Harper, Lamia; Balasubramanian, Divya; Ohneck, Elizabeth A et al. (2018) Staphylococcus aureus Responds to the Central Metabolite Pyruvate To Regulate Virulence. MBio 9:
Berger, Ashton C; Korkut, Anil; Kanchi, Rupa S et al. (2018) A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. Cancer Cell 33:690-705.e9

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