The Melanoma Program was created in 2002 and is comprised of 19 investigators, representing 11 departments of the New York University School of Medicine. Its core mission is to utilize the cohesive and unique interdisciplinary nature of its members to: 1) identify risk factors and prognostic markers of melanoma progression;2) evaluate the biologic heterogeneity of melanoma, including expression, furiction and molecular alterations of growth control pathways, oncogenes and antigens;and 3) integrate immunotherapeutic, chemotherapeutic and biological therapies into combination approaches for treating melanoma. The Program has three areas of unique strength which underlie these aims: a large clinical patient base, a translational research program that drives active research within the Program and prospectively accrues melanoma patients'blood, tissue specimens, and clinical information, and an immunotherapy program that tests novel cell-based approaches in combination with established or innovative therapies to treat melanoma patients. These common scientific interests and goals serve to foster vigorous interactions and collaborations between members of the Melanoma Program. Although this is a relatively young program, its members have produced over 100 melanoma-related publications, and intraprogrammatic collaborations and publications represent an increasing component every year. Total funding for this program is $2,444,482. Total publications for the past five years include 156 of which 6% are intra-programmatic and 26% are inter-programmatic.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-30
Application #
8038238
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2010-03-01
Budget End
2011-02-28
Support Year
30
Fiscal Year
2010
Total Cost
$24,476
Indirect Cost
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Pelzek, Adam J; Shopsin, Bo; Radke, Emily E et al. (2018) Human Memory B Cells Targeting Staphylococcus aureus Exotoxins Are Prevalent with Skin and Soft Tissue Infection. MBio 9:
Chiou, Kenneth L; Bergey, Christina M (2018) Methylation-based enrichment facilitates low-cost, noninvasive genomic scale sequencing of populations from feces. Sci Rep 8:1975
Jose, Cynthia C; Jagannathan, Lakshmanan; Tanwar, Vinay S et al. (2018) Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1. Mol Carcinog 57:794-806
Kourtis, Nikos; Lazaris, Charalampos; Hockemeyer, Kathryn et al. (2018) Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia. Nat Med 24:1157-1166
Formenti, Silvia C; Lee, Percy; Adams, Sylvia et al. (2018) Focal Irradiation and Systemic TGF? Blockade in Metastatic Breast Cancer. Clin Cancer Res 24:2493-2504
Snuderl, Matija; Kannan, Kasthuri; Pfaff, Elke et al. (2018) Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma. Nat Commun 9:2868
Stafford, James M; Lee, Chul-Hwan; Voigt, Philipp et al. (2018) Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma. Sci Adv 4:eaau5935
Lee, Chul-Hwan; Yu, Jia-Ray; Kumar, Sunil et al. (2018) Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin. Mol Cell 70:422-434.e6
Aiello, Nicole M; Maddipati, Ravikanth; Norgard, Robert J et al. (2018) EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration. Dev Cell 45:681-695.e4
Jung, Heekyung; Baek, Myungin; D'Elia, Kristen P et al. (2018) The Ancient Origins of Neural Substrates for Land Walking. Cell 172:667-682.e15

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