Center for Biospecimen Research & Development (CBRD) The Center for Biospecimen Research and Development (CBRD) was launched in 2015 and has replaced the BioRepository Center (BRC) shared resource presented at the last CCSG review on 2012. Under the direction of Andre Moreira, MD, PhD, Director of Surgical Pathology at NYU Langone Health (NYULH) and a recognized expert in lung pathology and biospecimen research, CBRD was created to support the increased demand across the NYULH research enterprise for standardized human biospecimens. CBRD focuses on improving the accessibility of human biospecimen resources to investigators and increasing institution-wide banking efforts and capacity. CBRD has implemented a campus-wide universal consent and policy for human biospecimen collection and storage to ensure regulatory compliance. CBRD provides well- annotated, high quality biospecimens that foster impactful translational research, thus guaranteeing the clinical relevance of basic findings. CBRD also supports the rapidly expanding portfolio of Perlmutter Cancer Center (PCC) investigator initiated clinical trials by facilitating acquisition, processing and distribution of biospecimens from enrolled patients. All of the samples collected are linked to clinical information obtained in our electronic medical record, EPIC.
The Specific Aims of CBRD are:
Aim 1) To maintain and expand a prospective Biospecimen Repository of PCC patient samples, as well as maintain and expand its linked clinicopathological information;
Aim 2) To process biospecimens, including by carrying out nucleic acid extraction and provide specialized Pathology support;
Aim 3) To stimulate collaborations involving the distribution of human biospecimens;
and Aim 4) To apply high quality control that meets national and international standards, as well as governance over biospecimen utilization.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016087-40
Application #
10124311
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-12-01
Project End
2024-02-29
Budget Start
2021-03-01
Budget End
2022-02-28
Support Year
40
Fiscal Year
2021
Total Cost
Indirect Cost
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Snetkova, Valentina; Skok, Jane A (2018) Enhancer talk. Epigenomics 10:483-498
Litwinoff, Evelyn M S; Gold, Merav Y; Singh, Karan et al. (2018) Myeloid ATG16L1 does not affect adipose tissue inflammation or body mass in mice fed high fat diet. Obes Res Clin Pract 12:174-186
Lee, Chul-Hwan; Holder, Marlene; Grau, Daniel et al. (2018) Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2. Mol Cell 70:435-448.e5
Fan, Xiaozhou; Alekseyenko, Alexander V; Wu, Jing et al. (2018) Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study. Gut 67:120-127
Gregory, Ann C; Sullivan, Matthew B; Segal, Leopoldo N et al. (2018) Smoking is associated with quantifiable differences in the human lung DNA virome and metabolome. Respir Res 19:174
Taylor, Martin S; Altukhov, Ilya; Molloy, Kelly R et al. (2018) Dissection of affinity captured LINE-1 macromolecular complexes. Elife 7:
Bertrand, Anne; Baron, Maria; Hoang, Dung M et al. (2018) In Vivo Evaluation of Neuronal Transport in Murine Models of Neurodegeneration Using Manganese-Enhanced MRI. Methods Mol Biol 1779:527-541
Jung, Seungyoun; Allen, Naomi; Arslan, Alan A et al. (2018) Anti-Müllerian hormone and risk of ovarian cancer in nine cohorts. Int J Cancer 142:262-270
Wang, Sophia S; Carrington, Mary; Berndt, Sonja I et al. (2018) HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. Cancer Res 78:4086-4096
Kirkling, Margaret E; Cytlak, Urszula; Lau, Colleen M et al. (2018) Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Rep 23:3658-3672.e6

Showing the most recent 10 out of 1170 publications