Abstract

The University of Pennsylvania Cancer Center (UPCC) is a multidisciplinary program in cancer research, education, clinical care, and community service. It is one component of the Fox Chase/University of Pennsylvania Comprehensive Cancer Center. Based inthe School of Medicine, the UPCC involves faculty from many schools of the University. It includes four major research divisions, each with distinct research programs: Clinical Research, Fundamental Research, Human REsources Research, and Epidemiology/Biostatistics Research. Shared Resources serve these various programs. Clinical Research encompasses a broad Clinical Trials Program and specific programmatic efforts in Nutrition and in Melanoma. Fundamental Research includes Immunobiology, Hematopoietic Cell Biology, and Molecular Genetics. Human Resources Research includes the Psychosocial and Palliative Care Research Programs and research in Health Care Economics. Epidemiology and Biostatistics encompasses Epidemiology Research, Biostatistics Research, the Center's patienbt data base and a Biostatistics Consulting Unit, one of nine Shared Resources within the UPCC. Other Shared Resources are the Clinical Trials Data Center, the Oncology Study (Inpatient) Unit, the Nutrition Core, the Pharmacology Core Laboratory, the Cell (Tissue Culture) Center, the Fluorescence Division of Human Resources Research. Interdisciplinary cancer education programs fostered by the Center supplement departmental efforts in cancer education. Extension of the Center's research and education programs into the the community serve the goals of cancer control. The Center's developmental efforts are directed toward expanding Epidemiology; continuing the growth of Molecular Genetics; building research related to Membrane Receptors; bridging the clinical and fundamental research programs related to Human Leukemia; and extending psychosocial research to include Biologic Studies relevant to human behavior. This application requests core support for the Center's research programs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA016520-11
Application #
3101586
Study Section
Cancer Center Support Grant Review Committee (CCS)
Project Start
1978-12-01
Project End
1987-11-30
Budget Start
1985-12-01
Budget End
1986-11-30
Support Year
11
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Waxman, Adam J; Clasen, Suparna; Hwang, Wei-Ting et al. (2018) Carfilzomib-Associated Cardiovascular Adverse Events: A Systematic Review and Meta-analysis. JAMA Oncol 4:e174519
Han, Joseph; Lachance, Catherine; Ricketts, M Daniel et al. (2018) The scaffolding protein JADE1 physically links the acetyltransferase subunit HBO1 with its histone H3-H4 substrate. J Biol Chem 293:4498-4509
Reshef, Ran; Ganetsky, Alex; Acosta, Edward P et al. (2018) Extended CCR5 Blockade for Graft-versus-Host Disease Prophylaxis Improves Outcomes of Reduced-Intensity Unrelated Donor Hematopoietic Cell Transplantation: A Phase II Clinical Trial. Biol Blood Marrow Transplant :
Gangadhar, Tara C; Savitch, Samantha L; Yee, Stephanie S et al. (2018) Feasibility of monitoring advanced melanoma patients using cell-free DNA from plasma. Pigment Cell Melanoma Res 31:73-81
Rosenfeld, Aaron M; Meng, Wenzhao; Luning Prak, Eline T et al. (2018) ImmuneDB, a Novel Tool for the Analysis, Storage, and Dissemination of Immune Repertoire Sequencing Data. Front Immunol 9:2107
Lang, Fengchao; Sun, Zhiguo; Pei, Yonggang et al. (2018) Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy. PLoS Pathog 14:e1007253
Buljan, Vlado A; Graeber, Manuel B; Holsinger, R M Damian et al. (2018) Calcium-axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes. J Biol Phys 44:53-80
Kushner, Carolyn J; Hwang, Wei-Ting; Wang, Shiyu et al. (2018) Long-term risk of second malignancies in women after breast conservation therapy for ductal carcinoma in situ or early-stage breast cancer. Breast Cancer Res Treat 170:45-53
Chang, Changgee; Kundu, Suprateek; Long, Qi (2018) Scalable Bayesian variable selection for structured high-dimensional data. Biometrics :
Min, Eun Jeong; Safo, Sandra E; Long, Qi (2018) Penalized Co-Inertia Analysis with Applications to -Omics Data. Bioinformatics :

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