Since its establishment in 1978, the Biostatistics Unit has been continuously funded by the NCI Core Grant. During the current project period, the Biostatistics Unit has been fully reorganized and a number of highly experienced faculty and staff biostatisticians have been recruited. In 1996, Jesse Berlin, ScD, Associate Professor of Biostatistics and Epidemiology, was appointed. Facility Director to lead this reorganization and expansion. In mid-1997, J. Richard Landis, PhD, a national expert in large scale, multi-center data coordinating projects, was recruited to Penn as Director of the Division of Biostatistics and Associate Director of the Biostatistics Unit. He significantly expanded the capabilities of the Cancer Center Biostatistics Unit to include comprehensive computing resources that are required to support cancer research projects involving the collection and analysis of extensive data. Instrumental to these changes was the senior leadership provided by John H. Glick, MD, Cancer Center Director, and Brian L. Strom, MD, MPH, a long-standing Cancer Center member who was appointed the first Chair of the Department of Biostatistics and Epidemiology in 1995. Considerable institutional and Cancer Center non-Core Grant resources as well as Departmental support have contributed to the recruitment of new biostatistics faculty and staff, new and expanded facilities and extensive statistical computing capabilities. Today, the research projects in multiple Cancer Center Research Programs. It plays an integral role within the Cancer Center's Clinical Trials Scientific Review and Monitoring Committee with a high degree of representation and authority. A significant number of the grant applications that received biostatistical input from the Biostatistics Unit during the current period have subsequently received peer-reviewed funding. This includes four NIH P01s. Based on internal and expert external reviews conducted by the Cancer Center since the reorganization, the new Biostatistics Unit has become an outstanding, well-utilized and respected Shared Resource that contributes significantly to the successful competition of peer-reviewed grant applications requiring high quality biostatistical support.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA016520-25
Application #
6300083
Study Section
Project Start
2000-02-04
Project End
2000-11-30
Budget Start
Budget End
Support Year
25
Fiscal Year
2000
Total Cost
$276,694
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Waxman, Adam J; Clasen, Suparna; Hwang, Wei-Ting et al. (2018) Carfilzomib-Associated Cardiovascular Adverse Events: A Systematic Review and Meta-analysis. JAMA Oncol 4:e174519
Han, Joseph; Lachance, Catherine; Ricketts, M Daniel et al. (2018) The scaffolding protein JADE1 physically links the acetyltransferase subunit HBO1 with its histone H3-H4 substrate. J Biol Chem 293:4498-4509
Reshef, Ran; Ganetsky, Alex; Acosta, Edward P et al. (2018) Extended CCR5 Blockade for Graft-versus-Host Disease Prophylaxis Improves Outcomes of Reduced-Intensity Unrelated Donor Hematopoietic Cell Transplantation: A Phase II Clinical Trial. Biol Blood Marrow Transplant :
Gangadhar, Tara C; Savitch, Samantha L; Yee, Stephanie S et al. (2018) Feasibility of monitoring advanced melanoma patients using cell-free DNA from plasma. Pigment Cell Melanoma Res 31:73-81
Rosenfeld, Aaron M; Meng, Wenzhao; Luning Prak, Eline T et al. (2018) ImmuneDB, a Novel Tool for the Analysis, Storage, and Dissemination of Immune Repertoire Sequencing Data. Front Immunol 9:2107
Lang, Fengchao; Sun, Zhiguo; Pei, Yonggang et al. (2018) Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy. PLoS Pathog 14:e1007253
Buljan, Vlado A; Graeber, Manuel B; Holsinger, R M Damian et al. (2018) Calcium-axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes. J Biol Phys 44:53-80
Kushner, Carolyn J; Hwang, Wei-Ting; Wang, Shiyu et al. (2018) Long-term risk of second malignancies in women after breast conservation therapy for ductal carcinoma in situ or early-stage breast cancer. Breast Cancer Res Treat 170:45-53
Chang, Changgee; Kundu, Suprateek; Long, Qi (2018) Scalable Bayesian variable selection for structured high-dimensional data. Biometrics :
Min, Eun Jeong; Safo, Sandra E; Long, Qi (2018) Penalized Co-Inertia Analysis with Applications to -Omics Data. Bioinformatics :

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