Abstract

of Shared ResourceThe Bioinformatics & Biotechnology Shared Resource provides a broad range of chemistry, biomolecular, andbioinformatics services and expertise in support of Cancer Center research programs. It includesBioinformatics, High-throughput DMA Sequencing & Genotyping, Functional Genomics, and Proteomics.Bioinformatics provides investigators with access to high-performance computing resources, bioinformaticssoftware, a software and database development group, and a staff of 10 Ph.D.-level bioinformatics experts.High-throughput DNA Sequencing & Genotyping provides investigators with access to automated DMAsequence analysis, fragment size analysis, and SNP detection technologies. Functional Genomics providescDNA and Affymetrix microarray services and analyses to Center investigators. Proteomics offers a range ofprotein chemistry capabilities including protein identification from a gel slice or spot; protein identification froma solution by LC-MS/MS; Intact mass measurement; and 2D-gel analysis. All of these resources are highlyintegrated and readily accessible using our Web-based on-line ordering, tracking, invoicing, and data retrievalsystem. In total, this shared resource staffing is now at 68 FTEs including 22 Ph.D.'s representing alldisciplines encompassed by the Shared Resource.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA021765-30
Application #
7714153
Study Section
Special Emphasis Panel (ZCA1-RTRB-Z (O1))
Project Start
2008-06-14
Project End
2013-02-28
Budget Start
2008-06-14
Budget End
2009-02-28
Support Year
30
Fiscal Year
2008
Total Cost
$536,297
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Donohoe, Clare; Bosi, Judy K; Sykes, April et al. (2018) Clinical Characteristics of Children and Adolescents Undergoing Hematopoietic Cell Transplantation Who Develop Oral Mucositis. Oncol Nurs Forum 45:457-462
Green, Daniel M; Wang, Mingjuan; Krasin, Matthew J et al. (2018) Serum ALT elevations in survivors of childhood cancer. A report from the St. Jude Lifetime Cohort Study. Hepatology :
Kirchhoff, Anne C; Nipp, Ryan; Warner, Echo L et al. (2018) ""Job Lock"" Among Long-term Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. JAMA Oncol 4:707-711
Crom, Deborah B; Ness, Kirsten K; Martinez, Larry R et al. (2018) Workplace experiences and turnover intention among adult survivors of childhood cancer. J Cancer Surviv 12:469-478
Bishop, Michael W; Advani, Shailesh M; Villarroel, Milena et al. (2018) Health-Related Quality of Life and Survival Outcomes of Pediatric Patients With Nonmetastatic Osteosarcoma Treated in Countries With Different Resources. J Glob Oncol :1-11
Heitzer, Andrew M; Ashford, Jason M; Hastings, Camden et al. (2018) Neuropsychological outcomes of patients with low-grade glioma diagnosed during the first year of life. J Neurooncol :
Tsujimoto, Shinichi; Osumi, Tomoo; Uchiyama, Meri et al. (2018) Diplotype analysis of NUDT15 variants and 6-mercaptopurine sensitivity in pediatric lymphoid neoplasms. Leukemia 32:2710-2714
Li, Liyuan; Qian, Maoxiang; Chen, I-Hsuan et al. (2018) Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice. Am J Pathol 188:656-671
Dvorak, Christopher C; Satwani, Prakash; Stieglitz, Elliot et al. (2018) Disease burden and conditioning regimens in ASCT1221, a randomized phase II trial in children with juvenile myelomonocytic leukemia: A Children's Oncology Group study. Pediatr Blood Cancer 65:e27034
Pui, Ching-Hon (2018) To delay or not to delay, that is the question for patients with acute lymphoblastic leukemia who do not receive prophylactic cranial irradiation. Cancer 124:4442-4446

Showing the most recent 10 out of 6764 publications