ADMINISTRATIVE CORE: ABSTRACT Karmanos Cancer Institute's (KCI) Administration is comprised of two integral parts: Cancer Center Administration and Senior Leadership. Cancer Center Administration provides a robust infrastructure that supports cancer research activities at KCI. The mission of Cancer Center Administration is to reliably and consistently provide cost-effective administrative services that further the conduct of efficient and effective research efforts. Overall responsibilities include fiscal accountability for the financial and operational activities of KCI, management of laboratory space, coordination of Shared Resources (Cores), management of information, assistance with faculty and personnel administration including coordination of faculty recruitment, coordination of institutional research projects, and the provision of necessary administrative support to the research related activities of KCI Leadership, Program Leaders, Shared Resources and the membership. CCSG funding of $147,682 is requested to support Administration. Notable accomplishments since the last grant submission include: ? Implementing significant upgrades to the Research Administration Application (RAA), the central repository of CCSG data, to ensure continuing compliance with latest NCI CCSG guidelines. ? Designing a Clinical Trials mobile app to display clinical trial information in real-time. ? Implementing iLab Solutions software for all CCSG Shared Resources. ? Expanding the marketing of CCSG Shared Resources through a Shared Resources handbook. ? Coordinating annual internal pilot project programs and the new Mock Study Section. ? Contributing to the integration of research and clinical operations with McLaren Health Care Corporation. Senior Leadership oversees the vision, mission and strategic plans for the KCI scientific community. The team ensures all KCI resources are optimally deployed to enhance the development of exceptional science. Senior Leadership is composed of scientific Associate Center Directors (ACDs) for Basic Sciences (Dr. Wei- Zen Wei), Clinical Sciences (Dr. Anthony Shields) and Population Sciences (Dr. Terrance Albrecht). They are supported by an ACD for Research Administration (Ms. Constance Claybaker) and overseen by the Deputy Center Director, Dr. Ann Schwartz. As President, CEO, and Center Director of the Karmanos Cancer Institute, Dr. Gerold Bepler bears ultimate responsibility for the administration and fiscal management of all KCI resources, including budgeting, personnel and faculty appointments, and space and equipment allocations. No CCSG funds are requested to support Senior Leadership activities.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA022453-34
Application #
8997269
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2016-02-01
Budget End
2016-11-30
Support Year
34
Fiscal Year
2016
Total Cost
$99,155
Indirect Cost
$34,489
Name
Wayne State University
Department
Type
DUNS #
001962224
City
Detroit
State
MI
Country
United States
Zip Code
48202
Feldmann, Daniel P; Cheng, Yilong; Kandil, Rima et al. (2018) In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells. J Control Release 276:50-58
Thakur, Manish K; Heilbrun, Lance; Dobson, Kimberlee et al. (2018) Phase I Trial of the Combination of Docetaxel, Prednisone, and Pasireotide in Metastatic Castrate-Resistant Prostate Cancer. Clin Genitourin Cancer 16:e695-e703
Wang, Zhaoxian; Sau, Samaresh; Alsaab, Hashem O et al. (2018) CD44 directed nanomicellar payload delivery platform for selective anticancer effect and tumor specific imaging of triple negative breast cancer. Nanomedicine 14:1441-1454
Vaishampayan, Ulka (2018) Advantages and Adversities of the Weighted Toxicity Score. Clin Cancer Res 24:4918-4920
Kim, Seongho; Wong, Weng Kee (2018) Extended two-stage adaptive designs with three target responses for phase II clinical trials. Stat Methods Med Res 27:3628-3642
Ravindra, Manasa; Wilson, Mike R; Tong, Nian et al. (2018) Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor ? and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis. J Med Chem 61:4228-4248
Beebe-Dimmer, Jennifer L; Albrecht, Terrance L; Baird, Tara E et al. (2018) The Detroit Research on Cancer Survivors (ROCS) Pilot Study: A focus on outcomes after cancer in a racially-diverse patient population. Cancer Epidemiol Biomarkers Prev :
Ahmed, Zainab Sabry Othman; Li, Xin; Li, Feng et al. (2018) Computational and biochemical studies of isothiocyanates as inhibitors of proteasomal cysteine deubiquitinases in human cancer cells. J Cell Biochem 119:9006-9016
Desai, Pinkal; Wallace, Robert; Anderson, Matthew L et al. (2018) An analysis of the effect of statins on the risk of Non-Hodgkin's Lymphoma in the Women's Health Initiative cohort. Cancer Med 7:2121-2130
White, Donna L; Hoogeveen, Ron C; Chen, Liang et al. (2018) A prospective study of soluble receptor for advanced glycation end products and adipokines in association with pancreatic cancer in postmenopausal women. Cancer Med 7:2180-2191

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