The Behavioral and Field Research Core (BFRC) is designed to facilitate the integration of communication and behavioral research across the Institute including work in epidemiology, cancer prevention, clinical and developmental therapeutics, palliative care, and genetics. The BFRC is grouped in the Population Research Core Cluster along with the Epidemiology Research Core. The Core offers expertise in communication science and behavioral research methodologies; design and evaluation of evidence-based social and behavioral interventions (including social marketing as a systematic approach to population level behavior change); social network methodology and analysis; quality of life measurement utilizing the most appropriate instruments; ecological momentary assessment (EMA techniques provide methods by which a research participant can report on symptoms, affect, behavior, and cognitions proximal to the experience, and these reports are obtained many times throughout the study); electronic daily diaries (QOL continues to be a critical factor in developmental therapeutic trials); and community engagement research, particularly related to health disparities. The Core maintains an active network of community organization partnerships across the Institute's catchment area. Community partners participate in research advisory committees and community advisory committees, providing community perspective, input and facilitating access to the populations they serve. Through these partnerships, the Core facilitates community access for Institute researchers, thus serving to assist in the translation and dissemination of cancer research. Resources available through BFRC include real-time video recording and coding of clinical interactions (including equipment, software and expertise), access to an extensive video archive for communication and behavioral studies, geographical and population tracking/mapping capabilities, community research participant registries, access to comprehensive national datasets (e.g. HINTS), as well as an extensive bank of clinical and social/behavioral instruments and measures. The services provided by the BFRC have contributed to 32 peer-reviewed publications during the current review period. As an example, the BFRC provided all regulatory tasks, recruitment, data collection, video capture, post-production editing, and coding for Dr. Penner's (PSDR) work demonstrating the importance of recognizing and understanding how the distinct dynamics of racially concordant and discordant interactions affect medical encounters and outcomes, (Hagiwara N, Soc SciMed, 2013).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA022453-38
Application #
9836633
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2019-12-01
Budget End
2020-11-30
Support Year
38
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
DUNS #
001962224
City
Detroit
State
MI
Country
United States
Zip Code
48202
Bao, Xun; Wu, Jianmei; Sanai, Nader et al. (2018) A liquid chromatography with tandem mass spectrometry method for quantitating total and unbound ceritinib in patient plasma and brain tumor. J Pharm Anal 8:20-26
Matherly, Larry H; Hou, Zhanjun; Gangjee, Aleem (2018) The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer. Cancer Chemother Pharmacol 81:1-15
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Heath, Elisabeth I; Lynce, Filipa; Xiu, Joanne et al. (2018) Racial Disparities in the Molecular Landscape of Cancer. Anticancer Res 38:2235-2240
McFall, Thomas; McKnight, Brooke; Rosati, Rayna et al. (2018) Progesterone receptor A promotes invasiveness and metastasis of luminal breast cancer by suppressing regulation of critical microRNAs by estrogen. J Biol Chem 293:1163-1177
McKnight, Brooke N; Viola-Villegas, Nerissa T (2018) Monitoring Src status after dasatinib treatment in HER2+ breast cancer with 89Zr-trastuzumab PET imaging. Breast Cancer Res 20:130
Greenwald, Mark K; Ruterbusch, Julie J; Beebe-Dimmer, Jennifer L et al. (2018) Risk of incident claims for chemotherapy-induced peripheral neuropathy among women with breast cancer in a Medicare population. Cancer :
Dyson, Greg; Farran, Batoul; Bolton, Susan et al. (2018) The extrema of circulating miR-17 are identified as biomarkers for aggressive prostate cancer. Am J Cancer Res 8:2088-2095
Shah, Seema; Brock, Ethan J; Jackson, Ryan M et al. (2018) Downregulation of Rap1Gap: A Switch from DCIS to Invasive Breast Carcinoma via ERK/MAPK Activation. Neoplasia 20:951-963

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