Abstract

This application requests a 5 year renewal of the Cancer Center Support Grant (CCSG) for the Arizona Cancer Center (ACC). The ACC was founded in 1976, has had a CCSG since 1978, and was designated as a Comprehensive Cancer Center by the NCI in 1990. The ACC functions as a matrix center and is a division of the University of Arizona (UA) College of Medicine (COM). The goal of the cancer center is to make major contributions to research related to the basic understanding, prevention, diagnosis, treatment and control of cancer as part of the NCI's network of Cancer Centers. The major established and proposed new programs of the ACC include Molecular Carcinogenesis, Cancer Treatment, Cancer Prevention and Control, Nursing Oncology, Cancer Diagnosis, Cancer Biology, and Immunobiology. In order to support and enhance the research programs, a series of 15 core support services have either already been established previously or proposed for implementation in this CCSG application. The shared resources requested include Analytical Chemistry, Biometry, Cytogenetics, Dishwashing, Experimental Radiation, Prevention and Control, Research Pharmacy, Tissue Culture, Flow Cytometry, Clinical Research, Molecular and Computational Biology, SCID Mouse Service, Transgenic Mouse Service and Pathology Research Services.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023074-18
Application #
2087109
Study Section
Cancer Center Support Review Committee (CCS)
Project Start
1978-09-01
Project End
1998-06-30
Budget Start
1995-08-15
Budget End
1996-06-30
Support Year
18
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Arizona
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721

  Publications

Knudsen, Erik S; Balaji, Uthra; Mannakee, Brian et al. (2018) Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility. Gut 67:508-520
Boese, Cody J; Nye, Jonathan; Buster, Daniel W et al. (2018) Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state. Mol Biol Cell 29:2874-2886
Sohail, Atif; Mushtaq, Adeela; Iftikhar, Ahmad et al. (2018) Emerging immune targets for the treatment of multiple myeloma. Immunotherapy 10:265-282
Doane, Cynthia J; Patil, Karuna; Hoffman, Emely A et al. (2018) Supernumerary Incisors in CB6F1 Mice Conditioned with Chemotherapy and Total Body Irradiation before Bone Marrow Transplantation. Comp Med 68:349-352
Bea, J W; Hsu, C-H; Blew, R M et al. (2018) Use of iDXA spine scans to evaluate total and visceral abdominal fat. Am J Hum Biol 30:
Lent, Adrienne B; O'Connor, Patrick A; Reikowsky, Ryan C et al. (2018) Quit outcomes among clients ineligible for cessation medication through the state quitline: a retrospective, observational study. BMC Public Health 18:1001
Bulkley, Joanna E; McMullen, Carmit K; Grant, Marcia et al. (2018) Ongoing ostomy self-care challenges of long-term rectal cancer survivors. Support Care Cancer 26:3933-3939
Zaim, Samir Rachid; Li, Qike; Schissler, A Grant et al. (2018) Emergence of pathway-level composite biomarkers from converging gene set signals of heterogeneous transcriptomic responses. Pac Symp Biocomput 23:484-495
Kobes, Joseph E; Georgiev, George I; Louis, Anthony V et al. (2018) A Comparison of Iron Oxide Particles and Silica Particles for Tracking Organ Recellularization. Mol Imaging 17:1536012118787322
Kelly, K R; Espitia, C M; Zhao, W et al. (2018) Oncolytic reovirus sensitizes multiple myeloma cells to anti-PD-L1 therapy. Leukemia 32:230-233

Showing the most recent 10 out of 1336 publications