The goal of the Experimental Mice Shared Service (EMSS) is to provide investigators at the Arizona Cancer Center with technical and scientific expertise in experimental mouse research with an emphasis on severe combined immune deficiency (scid) mouse models. Due to the need of investigations for experiments using other types of mice the service is expanding to include other mouse species (e.g. BALB/c, C3H, nude mice). The scid mice in the breeding colon and those scid mice used for experiments are separated with access to the breeding colony area being more restricted. All proposed mouse experiments/protocols are peer- reviewed by the Institutional Animal Care and Use Committee (IACUC). The IACUC consists of three community representatives, three laboratory veterinarians, one science librarian (non-scientific member), and 14 scientific peer researchers. The EMSS works in coordination with University Animal Control (UAC) and IACUC to provide quality veterinary care and prevention/detection of mouse diseases so that experiments can be completed in an efficient and scientifically sound manner.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA023074-22S1
Application #
6295867
Study Section
Project Start
1999-07-01
Project End
2000-06-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
22
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Arizona
Department
Type
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Knudsen, Erik S; Balaji, Uthra; Mannakee, Brian et al. (2018) Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility. Gut 67:508-520
Boese, Cody J; Nye, Jonathan; Buster, Daniel W et al. (2018) Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state. Mol Biol Cell 29:2874-2886
Sohail, Atif; Mushtaq, Adeela; Iftikhar, Ahmad et al. (2018) Emerging immune targets for the treatment of multiple myeloma. Immunotherapy 10:265-282
Doane, Cynthia J; Patil, Karuna; Hoffman, Emely A et al. (2018) Supernumerary Incisors in CB6F1 Mice Conditioned with Chemotherapy and Total Body Irradiation before Bone Marrow Transplantation. Comp Med 68:349-352
Bea, J W; Hsu, C-H; Blew, R M et al. (2018) Use of iDXA spine scans to evaluate total and visceral abdominal fat. Am J Hum Biol 30:
Lent, Adrienne B; O'Connor, Patrick A; Reikowsky, Ryan C et al. (2018) Quit outcomes among clients ineligible for cessation medication through the state quitline: a retrospective, observational study. BMC Public Health 18:1001
Bulkley, Joanna E; McMullen, Carmit K; Grant, Marcia et al. (2018) Ongoing ostomy self-care challenges of long-term rectal cancer survivors. Support Care Cancer 26:3933-3939
Zaim, Samir Rachid; Li, Qike; Schissler, A Grant et al. (2018) Emergence of pathway-level composite biomarkers from converging gene set signals of heterogeneous transcriptomic responses. Pac Symp Biocomput 23:484-495
Kobes, Joseph E; Georgiev, George I; Louis, Anthony V et al. (2018) A Comparison of Iron Oxide Particles and Silica Particles for Tracking Organ Recellularization. Mol Imaging 17:1536012118787322
Kelly, K R; Espitia, C M; Zhao, W et al. (2018) Oncolytic reovirus sensitizes multiple myeloma cells to anti-PD-L1 therapy. Leukemia 32:230-233

Showing the most recent 10 out of 1336 publications