Abstract

The Arizona Cancer Center Clinical Research Shared Service, directed by Thomas P. Miller, M.D., professor of medicine, has the overall mission of supporting and facilitating ACC clinical research initiatives for cancer treatment, prevention, screening, supportive care, and translational investigations. The shared services is organized into the following operational components: Clinical Trials Office (CTO), Clinical Data Management, Research Nursing, and the Arizona Cancer Center Clinical Research Information System Working Group. The Clinical Trials Office also assists the Arizona Cancer Center Scientific Review Committee (Protocol Review and Monitoring System). The benefits of centralization of clinical research services as detailed above include: availability of a mechanism for prioritization of studies and enforcement of peer review; improved internal and external awareness of protocols, programs, and treatment options available at the ACC; promotion of scientific communication and collaboration, standardization of research and resource management procedures.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023074-25
Application #
6659164
Study Section
Project Start
2002-09-06
Project End
2003-06-30
Budget Start
Budget End
Support Year
25
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
University of Arizona
Department
Type
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85722

  Publications

McLamarrah, Tiffany A; Buster, Daniel W; Galletta, Brian J et al. (2018) An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly. J Cell Biol 217:1217-1231
Mannakee, Brian K; Balaji, Uthra; Witkiewicz, Agnieszka K et al. (2018) Sensitive and specific post-call filtering of genetic variants in xenograft and primary tumors. Bioinformatics 34:1713-1718
Glassman, Caleb R; Parrish, Heather L; Lee, Mark S et al. (2018) Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex. Cell Rep 22:1263-1275
Nair, Uma S; Brady, Benjamin R; O'Connor, Patrick A et al. (2018) Factors Predicting Client Re-Enrollment in Tobacco Cessation Services in a State Quitline. Prev Chronic Dis 15:E126
Akam, E A; Utterback, R D; Marcero, J R et al. (2018) Disulfide-masked iron prochelators: Effects on cell death, proliferation, and hemoglobin production. J Inorg Biochem 180:186-193
Hadinger, Kyle P; Marshalek, Joseph P; Sheeran, Paul S et al. (2018) Optimization of Phase-Change Contrast Agents for Targeting MDA-MB-231 Breast Cancer Cells. Ultrasound Med Biol 44:2728-2738
Galbraith, David W; Sliwinska, Elwira; Samadder, Partha (2018) Nuclear Cytometry: Analysis of the Patterns of DNA Synthesis and Transcription Using Flow Cytometry, Confocal Microscopy, and RNA Sequencing. Methods Mol Biol 1678:371-392
Han, Jiali; Li, Jianrong; Achour, Ikbel et al. (2018) Convergent downstream candidate mechanisms of independent intergenic polymorphisms between co-classified diseases implicate epistasis among noncoding elements. Pac Symp Biocomput 23:524-535
Zeltzer, Sebastian; Zeltzer, Carol A; Igarashi, Suzu et al. (2018) Virus Control of Trafficking from Sorting Endosomes. MBio 9:
Nguyen, Mike M; Martinez, Jessica A; Hsu, Chiu-Hsieh et al. (2018) Bioactivity and prostate tissue distribution of metformin in a preprostatectomy prostate cancer cohort. Eur J Cancer Prev 27:557-562

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