9.1.12 BIOMETRY SHARED SERVICE The Biometry Shared Service (BSS) brings together expertise in biostatistics, clinical trials, epidemiology, applied mathematics, statistical computing, and database applications. Personnel in the BSS have wide-ranging involvement across the research activities ofthe Arizona Cancer Center (AZCC), including clinical, translational, basic, and population-based research. Biostatistical collaboration and consultation have been provided for investigators in each of the five Scientific Programs in the AZCC. As an example, for the period July 2006 - June 2008, Biometry personnel supported 62 AZCC Program Member investigators. The BSS is active in all phases of study design, operation, data management, statistical analysis, and manuscript preparation. Provided services include: 1) protocol development;2) review of Cancer Center protocols;3) data analysis and reporting;4) statistical database applications;5) data services and computer programming;6) education and training;and 7) statistical consultation and collaboration. Biostatisticians from the BSS are members of the Scientific Review Committee, which reviews Cancer Center patient protocols before activation to ensure appropriate scientific content. DUring the current funding period, biostatisticians have been co-authors on approximately 80 papers published by AZCC investigators. Additionally, 170 technical reports have been generated to document statistical analyses and their interpretation. Recruitment activities in Biometry are enhancing the breadth of biostatistical support of Cancer Center activities, allowing the fostering of the philosophy that productive research requires high quality biostatistical collaboration. Biometry faculty have had significant success in attracting funding for biostatistics-related Cores in a number of long-term research projects in the AZCC;in addition, BSS biostatisticians serve as co-investigators on numerous other funded studies. Collaboration of Biometry personnel with AZCC investigators on the design, conduct, analysis, and interpretation of cancer studies continues to enhance the quality of the research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023074-35
Application #
8540960
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
35
Fiscal Year
2013
Total Cost
$315,719
Indirect Cost
$107,682
Name
University of Arizona
Department
Type
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721
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Nair, Uma S; Bell, Melanie L; Yuan, Nicole P et al. (2018) Associations Between Comorbid Health Conditions and Quit Outcomes Among Smokers Enrolled in a State Quitline, Arizona, 2011-2016. Public Health Rep 133:200-206
Smithey, Megan J; Venturi, Vanessa; Davenport, Miles P et al. (2018) Lifelong CMV infection improves immune defense in old mice by broadening the mobilized TCR repertoire against third-party infection. Proc Natl Acad Sci U S A 115:E6817-E6825
Maisel, Sabrina; Broka, Derrick; Schroeder, Joyce (2018) Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration. Oncotarget 9:6463-6477
Daenthanasanmak, Anusara; Wu, Yongxia; Iamsawat, Supinya et al. (2018) PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity. J Clin Invest 128:2787-2801
Augustus, Gaius J; Ellis, Nathan A (2018) Colorectal Cancer Disparity in African Americans: Risk Factors and Carcinogenic Mechanisms. Am J Pathol 188:291-303

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