The Cancer Symptom Control Program consists of 17 Participating Members, representing total peer-reviewed funding for $4.14 Million annual direct costs ($5.65 Million in total costs). During the last two years, its members were responsible for a total of 100 cancer-relevant, peer-reviewed publications, 29% of which were intra- and inter- programmatic collaborations. This Program, formerly called """"""""Palliative Care"""""""", is dedicated to research on the impact of cancer on human consciousness and sensory experience. It is comprised of members who are conduct highly interlocking studies on the consequences of cancer and its treatment on the quality of life of the patient. These examine pain, fatigue, anxiety, depression and sleep fragmentation, caused by cancer and how these can best be ameliorated to improve quality of life and satisfaction with medical care. The studies also examine the efficience of communications between doctors and their patients and the effect of ethnic and cultural characteristics of the patients of the subjective experience of the disease. This Program brings to bear both basic and clinical research on mitigating the physical and mental anguish associated with cancer. Of course, the cancer patients themselves are the main beneficiaries of this research on symptom control, but their families with severe illnesses. Members of this Program have developed a series of studiers highly specific to cancer patients in terms of: (1) cancer pain syndromes; (2) fatigue and sleep in cancer patients, and; (3) quality of life in cancer patients.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA023100-18S1
Application #
6501417
Study Section
Subcommittee G - Education (NCI)
Project Start
2001-06-21
Project End
2002-04-30
Budget Start
Budget End
Support Year
18
Fiscal Year
2001
Total Cost
$183,723
Indirect Cost
Name
University of California San Diego
Department
Type
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Singh, Siddharth; Loomba, Rohit (2018) Role of two-dimensional shear wave elastography in the assessment of chronic liver diseases. Hepatology 67:13-15
Hartman, Sheri J; Nelson, Sandahl H; Myers, Emily et al. (2018) Randomized controlled trial of increasing physical activity on objectively measured and self-reported cognitive functioning among breast cancer survivors: The memory & motion study. Cancer 124:192-202
Hoffmann, Hanne M; Gong, Ping; Tamrazian, Anika et al. (2018) Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner. Mol Cell Endocrinol 461:143-154
Liu, Xuxiang; Cao, Minghui; Palomares, Melanie et al. (2018) Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts. Breast Cancer Res 20:127
Huang, Justin K; Carlin, Daniel E; Yu, Michael Ku et al. (2018) Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. Cell Syst 6:484-495.e5
Kalyanaraman, Hema; Schwaerzer, Gerburg; Ramdani, Ghania et al. (2018) Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes. Diabetes 67:607-623
Hartman, Sheri J; Marinac, Catherine R; Cadmus-Bertram, Lisa et al. (2018) Sedentary Behaviors and Biomarkers Among Breast Cancer Survivors. J Phys Act Health 15:1-6
Wu, Yan; Tamayo, Pablo; Zhang, Kun (2018) Visualizing and Interpreting Single-Cell Gene Expression Datasets with Similarity Weighted Nonnegative Embedding. Cell Syst 7:656-666.e4
Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888
Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306

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