The Digital Imaging and Cell Microinjection (DICM) Shared Resource comprises valuable and modern tools which are made available as routine services to Cancer Center Members. Services include high-resolution digital deconvolution microscopy, digital epi-fluorescence and brightfield microscopy, quantitative image analysis, cell microinjection and subsequent biological analyses, photo-production and training and advice. These services have been crucial for individual lab projects, intra- programmatic research and inter-programmatic research. As research goals and efforts within our Center which address our molecular and cellular functions and intracellular localization of genes implicated in the genesis or growth modulation of cancer cells are emerging with increasing frequency, the Center has taken steps to provide cost-effective support for these cellular and tissue-based studies. This evolution stems from the fact that investigators, such as those in our Cancer Biology and clinical investigation. Programs, have been identifying candidate candidate genes which may be responsible. This has reinforced the fact that the highly important task of solving the functions of these genes is often rate limiting, which is an essential feature of the above programs as well as others in our Center. As clues to the functions of candidate genes are often gained by studying the location of the gene products in cells, the DICM Shared Resource meets a portion of these needs. According, the Resource has been used by over 30 laboratories within the Cancer Center.
| Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888 |
| Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306 |
| Murzin, Vyacheslav L; Woods, Kaley; Moiseenko, Vitali et al. (2018) 4? plan optimization for cortical-sparing brain radiotherapy. Radiother Oncol 127:128-135 |
| Norton, Jeffrey A; Kim, Teresa; Kim, Joseph et al. (2018) SSAT State-of-the-Art Conference: Current Surgical Management of Gastric Tumors. J Gastrointest Surg 22:32-42 |
| Ikeda, Sadakatsu; Tsigelny, Igor F; Skjevik, Åge A et al. (2018) Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma. Oncologist 23:586-593 |
| Buckley, Alexandra R; Ideker, Trey; Carter, Hannah et al. (2018) Exome-wide analysis of bi-allelic alterations identifies a Lynch phenotype in The Cancer Genome Atlas. Genome Med 10:69 |
| Parish, Austin J; Nguyen, Vi; Goodman, Aaron M et al. (2018) GNAS, GNAQ, and GNA11 alterations in patients with diverse cancers. Cancer 124:4080-4089 |
| Xu, Selene; Thompson, Wesley; Ancoli-Israel, Sonia et al. (2018) Cognition, quality-of-life, and symptom clusters in breast cancer: Using Bayesian networks to elucidate complex relationships. Psychooncology 27:802-809 |
| Tao, Li; Schwab, Richard B; San Miguel, Yazmin et al. (2018) Breast Cancer Mortality in Older and Younger Breast Cancer Patients in California. Cancer Epidemiol Biomarkers Prev : |
| Sagredo, Eduardo A; Blanco, Alejandro; Sagredo, Alfredo I et al. (2018) ADAR1-mediated RNA-editing of 3'UTRs in breast cancer. Biol Res 51:36 |
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