The mission of the Cancer Control Program is to promote collaborative research to reduce cancer risk and mortality and to enhance the quality of life of cancer patients. The Program fosters research across three thematic areas: (1) Prevention/risk reduction;(2) Screening/early detection;and (3) Quality of life/quality of care. Cross-cutting themes include research on communications, and translation/dissemination/adoption, with a developing health services research theme. The Program consists of 21 members from 10 departments accounting for $6.6 million in total funding, of which $4 million is from the NCI. This group of investigators has published 268 peer-reviewed manuscripts during the current funding period, of which 88 (33%) were joint publications with other programs, indicating a high degree of inter-programmatic collaboration, a substantial increase in such activity since the last review. In addition, 79 (29%) of the publications were intra-programmatic, reflecting collaborative work among our 21 program members. Program highlights include novel findings in all three thematic areas. Prevention researchers have published and disseminated findings from a trial to promote sun-safe behaviors among adolescents. They have published research showing a relation between exposure to smoking in movies and adolescent smoking, research that forms the basis for a public health campaign to reduce movie smoking depictions. Screening researchers lead one of 5 mammography registries in the U.S. and are disseminating successful interventions to promote cancer screening in primary care. Program members ask penetrating questions about the utility of current approaches to cancer screening, given issues such as over-diagnosis bias. Quality-of-life researchers have published novel findings on the adverse effects of cancer treatments on cognitive function, showing also that the epsilon 4 allele of APOE is associated with higher risk for this complication. Communications researchers are devising effective ways to discuss treatment and medication decisions with patients and working with the FDA to disseminate them. We are building our capacity to do research in communications and health services delivery through a recruitment and mentorship program. Program leaders host regular meetings among members and across programs to foster collaboration and ensure mentorship of young investigators, and members participate in a T32 Ph.D. training program in health services research. Going forward, the Program anticipates additional recruitment and continued expansion in areas of strength, including research into media influences on cancer risk behaviors, mammography research, and dissemination of practice systems of care to support cancer screening.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA023108-31
Application #
7944592
Study Section
Subcommittee G - Education (NCI)
Project Start
2009-04-21
Project End
2013-11-30
Budget Start
2009-04-21
Budget End
2009-11-30
Support Year
31
Fiscal Year
2009
Total Cost
$75,460
Indirect Cost
Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Svedbom, Axel; Borgström, Fredrik; Hernlund, Emma et al. (2018) Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS. Qual Life Res 27:707-716
Skolasky, Richard L; Scherer, Emily A; Wegener, Stephen T et al. (2018) Does reduction in sciatica symptoms precede improvement in disability and physical health among those treated surgically for intervertebral disc herniation? Analysis of temporal patterns in data from the Spine Patient Outcomes Research Trial. Spine J 18:1318-1324
Doubeni, Chyke A; Gabler, Nicole B; Wheeler, Cosette M et al. (2018) Timely follow-up of positive cancer screening results: A systematic review and recommendations from the PROSPR Consortium. CA Cancer J Clin 68:199-216
Sites, Brian D; Harrison, Jordon; Herrick, Michael D et al. (2018) Prescription Opioid Use and Satisfaction With Care Among Adults With Musculoskeletal Conditions. Ann Fam Med 16:6-13
Li, Bo; Wang, Yanru; Xu, Yinghui et al. (2018) Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. Int J Cancer 142:2303-2312
Mittmann, Nicole; Stout, Natasha K; Tosteson, Anna N A et al. (2018) Cost-effectiveness of mammography from a publicly funded health care system perspective. CMAJ Open 6:E77-E86
Landon, Bruce E; Keating, Nancy L; Onnela, Jukka-Pekka et al. (2018) Patient-Sharing Networks of Physicians and Health Care Utilization and Spending Among Medicare Beneficiaries. JAMA Intern Med 178:66-73
Ghali, Fady; Celaya, Maria; Laviolette, Michael et al. (2018) Does Travel Time to a Radiation Facility Impact Patient Decision-Making Regarding Treatment for Prostate Cancer? A Study of the New Hampshire State Cancer Registry. J Rural Health 34 Suppl 1:s84-s90
Yang, Wei; Hosford, Sarah R; Traphagen, Nicole A et al. (2018) Autophagy promotes escape from phosphatidylinositol 3-kinase inhibition in estrogen receptor-positive breast cancer. FASEB J 32:1222-1235
Buckey, Jay C; Phillips, Scott D; Anderson, Allison P et al. (2018) Microgravity-induced ocular changes are related to body weight. Am J Physiol Regul Integr Comp Physiol 315:R496-R499

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