Abstract

Since January 1996, a scientific review committee (Clinical Cancer Research Committee?CCRC) and a Safety and Data Monitoring Committee (SDMC) have functioned at Norris Cotton Cancer Center. The CCRC reviews each new clinical trial protocol prior to Institutional Review Board (IRB) review, and the SDMC monitors safety and data integrity on a regular basis throughout the trial. Prior to IRB review, the NCCC Office of Clinical Research (OCR) submits the protocol to the CCRC. The CCRC is responsible for the scientific review of all new studies involving cancer patients or cancer prevention in human subjects. This assessment involves a review of all scientific aspects of the study, including the required safety and data monitoring plan. Once a protocol receives CCRC and IRB approval, the protocol is considered open for activation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023108-32
Application #
8015012
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2009-12-01
Budget End
2010-11-30
Support Year
32
Fiscal Year
2010
Total Cost
$49,363
Indirect Cost

  Institution

Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755

  Publications

Geller, Berta M; Frederick, Paul D; Knezevich, Stevan R et al. (2018) Pathologists' Use of Second Opinions in Interpretation of Melanocytic Cutaneous Lesions: Policies, Practices, and Perceptions. Dermatol Surg 44:177-185
Yeager, Mark P; Guyre, Cheryl A; Sites, Brian D et al. (2018) The Stress Hormone Cortisol Enhances Interferon-?-Mediated Proinflammatory Responses of Human Immune Cells. Anesth Analg 127:556-563
Courtney, Andrea L; Rapuano, Kristina M; Sargent, James D et al. (2018) Reward System Activation in Response to Alcohol Advertisements Predicts College Drinking. J Stud Alcohol Drugs 79:29-38
Aschbrenner, Kelly A; Bobak, Carly; Schneider, Emily J et al. (2018) Egocentric social networks and smoking among adults with serious mental illness. Transl Behav Med 8:531-539
Tapp, Stephanie J; Martin, Brook I; Tosteson, Tor D et al. (2018) Understanding the value of minimally invasive procedures for the treatment of lumbar spinal stenosis: the case of interspinous spacer devices. Spine J 18:584-592
Rodriguez-Garcia, Marta; Fortier, Jared M; Barr, Fiona D et al. (2018) Isolation of Dendritic Cells from the Human Female Reproductive Tract for Phenotypical and Functional Studies. J Vis Exp :
Shee, Kevin; Yang, Wei; Hinds, John W et al. (2018) Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. J Exp Med 215:895-910
Gareen, Ilana F; Black, William C; Tosteson, Tor D et al. (2018) Medical Care Costs Were Similar Across the Low-dose Computed Tomography and Chest X-Ray Arms of the National Lung Screening Trial Despite Different Rates of Significant Incidental Findings. Med Care 56:403-409
Kuklinski, Lawrence F; Yan, Shaofeng; Li, Zhongze et al. (2018) VISTA expression on tumor-infiltrating inflammatory cells in primary cutaneous melanoma correlates with poor disease-specific survival. Cancer Immunol Immunother 67:1113-1121
Ji, Xiangming; Niu, Xinnan; Qian, Jun et al. (2018) A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol 58:777-779

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