Genomics & Molecular Biology Shared Resource The Genomics & Molecular Biology Shared Resource (GMBSR) was created in 2013 by combining the Genomics Shared Resource with the Molecular Biology Shared Resource. The merger enhanced the communication between the cores, maximized the utilization of staff expertise, and raised the quality of services offered to researchers. The GMBSR offers next generation sequencing (Ion Torrent and Illumina) and Sanger sequencing in addition to microarray services (Illumina and Affymetrix), NanoString technology, and shared instrumentation, including qPCR thermocyclers. Mandatory free consultation regarding experimental design and budget estimates are provided to every researcher initiating a new project. The GMBSR is directed by Craig Tomlinson, PhD, with Genomics located in Lebanon at the Norris Cotton Cancer Center (NCCC), while Molecular Biology is based on the Hanover campus. Genomics, overseen by Co-Director Joanna Hamilton, PhD, includes an experienced technician and a bioinformaticist. Molecular Biology is led by Co- Director Dr. Yolanda Sanchez, PhD, and is staffed by a Senior Technician/Manager and a technical specialist. The GMBSR is the most widely used NCCC Shared Resource, supporting over 170 biomedical laboratories in the Dartmouth research community, of which approximately one-half are laboratories led by NCCC investigators in five of the six NCCC Research Programs (Cancer Epidemiology, Cancer Mechanisms, Molecular Therapeutics, Cancer Imaging & Radiobiology, and Immunology & Cancer Immunotherapy). The rapidly changing field of Genomics presents unique challenges to the GMBSR. To meet the needs of and to inform NCCC investigators, the GMBSR conduct workshops, present at laboratory meetings and tumor boards; speak at local seminars, and attend national and regional technology conferences to learn the latest technologies, techniques, and methods.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA023108-36
Application #
8804005
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-08-04
Project End
2019-11-30
Budget Start
2015-02-19
Budget End
2015-11-30
Support Year
36
Fiscal Year
2015
Total Cost
$170,982
Indirect Cost
$65,438
Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Soneji, Samir S; Sung, Hai-Yen; Primack, Brian A et al. (2018) Quantifying population-level health benefits and harms of e-cigarette use in the United States. PLoS One 13:e0193328
Durand, Marie-Anne; Yen, Renata West; O'Malley, A James et al. (2018) What matters most: protocol for a randomized controlled trial of breast cancer surgery encounter decision aids across socioeconomic strata. BMC Public Health 18:241
Courtney, Andrea L; Rapuano, Kristina M; Sargent, James D et al. (2018) Brain Reward Responses Are Behaviorally Relevant: The Authors Respond. J Stud Alcohol Drugs 79:41-42
Tosteson, Anna N A; Yang, Qian; Nelson, Heidi D et al. (2018) Second opinion strategies in breast pathology: a decision analysis addressing over-treatment, under-treatment, and care costs. Breast Cancer Res Treat 167:195-203
Molodtsov, Aleksey; Turk, Mary Jo (2018) Tissue Resident CD8 Memory T Cell Responses in Cancer and Autoimmunity. Front Immunol 9:2810
Elder, David E; Piepkorn, Michael W; Barnhill, Raymond L et al. (2018) Pathologist characteristics associated with accuracy and reproducibility of melanocytic skin lesion interpretation. J Am Acad Dermatol 79:52-59.e5
Rutter, Carolyn M; Kim, Jane J; Meester, Reinier G S et al. (2018) Effect of Time to Diagnostic Testing for Breast, Cervical, and Colorectal Cancer Screening Abnormalities on Screening Efficacy: A Modeling Study. Cancer Epidemiol Biomarkers Prev 27:158-164
Lin, Anping; Yin, Juan; Cheng, Chao et al. (2018) Decreased expression of FOXA2 promotes eutopic endometrial cell proliferation and migration in patients with endometriosis. Reprod Biomed Online 36:181-187
Punshon, Tracy; Jackson, Brian P (2018) Essential micronutrient and toxic trace element concentrations in gluten containing and gluten-free foods. Food Chem 252:258-264
Pernas, Sonia; Martin, Miguel; Kaufman, Peter A et al. (2018) Balixafortide plus eribulin in HER2-negative metastatic breast cancer: a phase 1, single-arm, dose-escalation trial. Lancet Oncol 19:812-824

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