Abstract

) The Protocol Review and Monitoring System (Scientific Review Committee - SRC) of the UNMC Eppley Cancer Center was formed in 1996. In September of 1997 the Chancellor of UNMC mandated that all cancer-related protocols be formally reviewed and approved by the SRC prior to being approved for accrual by the Institutional Review Board. The SRC also reviews all previously existing active cancer protocols for formal SRC approval prior to receiving renewal approval by the IRB. The SRC performs annual review of all cancer-related protocols. The Committee also reviews changes to investigator initiated or industry sponsored protocols before continued accrual can occur. The SRC has the authority to terminate cancer protocols under specific guidelines. The SRC meets monthly at least ten days prior to the IRB meeting. Expedited SRC review requests are coordinated through the SRC chair. The SRC reviewed 140 cancer-related protocols in 1998. The SRC is committed to peer reviewed clinical cancer research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA036727-16
Application #
6404383
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
1995-08-28
Project End
2004-07-31
Budget Start
Budget End
Support Year
16
Fiscal Year
2000
Total Cost
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Tian, Tian; Bi, Chengfeng; Hein, Ashley L et al. (2018) Rac1 is a novel therapeutic target in mantle cell lymphoma. Blood Cancer J 8:17
Saxena, Sugandha; Purohit, Abhilasha; Varney, Michelle L et al. (2018) Semaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells. BMC Cancer 18:1283
Chatterjee, Arpita; Zhu, Yuxiang; Tong, Qiang et al. (2018) The Addition of Manganese Porphyrins during Radiation Inhibits Prostate Cancer Growth and Simultaneously Protects Normal Prostate Tissue from Radiation Damage. Antioxidants (Basel) 7:
Wehrkamp, Cody J; Natarajan, Sathish Kumar; Mohr, Ashley M et al. (2018) miR-106b-responsive gene landscape identifies regulation of Kruppel-like factor family. RNA Biol 15:391-403
Chhonker, Yashpal S; Sleightholm, Richard L; Li, Jing et al. (2018) Simultaneous quantitation of hydroxychloroquine and its metabolites in mouse blood and tissues using LC-ESI-MS/MS: An application for pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci 1072:320-327
Lopez, Wilfredo; Page, Alexis M; Carlson, Darby J et al. (2018) Analysis of immune-related genes during Nora virus infection of Drosophila melanogaster using next generation sequencing. AIMS Microbiol 4:123-139
Iseka, Fany M; Goetz, Benjamin T; Mushtaq, Insha et al. (2018) Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function. J Immunol 200:483-499
Barger, Carter J; Zhang, Wa; Sharma, Ashok et al. (2018) Expression of the POTE gene family in human ovarian cancer. Sci Rep 8:17136
Huang, Yunlong; Li, Yuju; Zhang, Hainan et al. (2018) Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869. Cell Discov 4:19
Kumar, Vinod; Kumar, Virender; Chaudhary, Amit Kumar et al. (2018) Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis. Mol Ther Nucleic Acids 12:490-503

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