Abstract

The NMR Shared Resource provides the infrastructure for the acquisition of NMR data and the determination of structures of biological molecules. The Varian INOVA 500-MHz NMR magnet, with its new console and probes are located in room 1009 of the Eppley Science Hall. The new Varian INOVA 600-MHz instrument is in the adjacent room (1010 ESH) and the two rooms have been connected with an opening. The 500-MHz NMR instrument has been upgraded with a new console and associated probes to make it state-of-the-art and compatible with the 600 instrument. A cold probe has been ordered for the 600 instrument, which will provide a significant increase in signal to noise and sensitivity. The facility is directed by Dr. Gus Wang (Assistant Professor, Eppley Institute, UNMC), with the support of Paul Keifer, Ph.D. (Research Assistant Professor, Eppley Institute), who maintains the infrastructure and provides user support. Cancer Center members with peer-reviewed funding account for 18% of the facility's usage.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA036727-20
Application #
6998297
Study Section
Subcommittee G - Education (NCI)
Project Start
2004-09-20
Project End
2009-07-31
Budget Start
2004-09-20
Budget End
2005-07-31
Support Year
20
Fiscal Year
2004
Total Cost
$36,321
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Svechkarev, Denis; Mohs, Aaron M (2018) Organic fluorescent dye-based nanomaterials: Advances in the rational design for imaging and sensing applications. Curr Med Chem :
Berger, Ann M; Kupzyk, Kevin A; Djalilova, Dilorom M et al. (2018) Breast Cancer Collaborative Registry informs understanding of factors predicting sleep quality. Support Care Cancer :
Wang, Ying; Mirza, Sameer; Wu, Shaohua et al. (2018) 3D hydrogel breast cancer models for studying the effects of hypoxia on epithelial to mesenchymal transition. Oncotarget 9:32191-32203
Qi, Dianjun; Wu, Shaohua; Lin, Haishuang et al. (2018) Establishment of a Human iPSC- and Nanofiber-Based Microphysiological Blood-Brain Barrier System. ACS Appl Mater Interfaces 10:21825-21835
Schopfer, Lawrence M; Lockridge, Oksana (2018) Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity. J Biol Chem 293:13566-13577
Neilsen, Beth K; Chakraborty, Binita; McCall, Jamie L et al. (2018) WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage. BMC Cancer 18:673
Khadge, Saraswoti; Sharp, John Graham; Thiele, Geoffrey M et al. (2018) Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology. J Nutr Biochem 52:92-102
Baranovskiy, Andrey G; Duong, Vincent N; Babayeva, Nigar D et al. (2018) Activity and fidelity of human DNA polymerase ? depend on primer structure. J Biol Chem 293:6824-6843
Ingersoll, Matthew A; Chou, Yu-Wei; Lin, Jamie S et al. (2018) p66Shc regulates migration of castration-resistant prostate cancer cells. Cell Signal 46:1-14
Kuss, Mitchell; Kim, Jiyoung; Qi, Dianjun et al. (2018) Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function. Acta Biomater 71:486-495

Showing the most recent 10 out of 1372 publications