Abstract

The Safety Shared Resource is critical to the safe use of toxic agents in investigators' laboratories and in the Animal Care Shared Resource. The safety program in the UNMC/Eppley Cancer Center is based on general guidelines described in the """"""""National Cancer Institute Safety Standard for Research Involving Chemical Carcinogens"""""""" (NIH 76-900). These guidelines are supplemented by specific safety regulations prepared by the Safety Committee to govern the use of hazardous, toxic, carcinogenic, mixed waste and biohazardous materials. The policies and regulations of the Safety Shared Resource extend the UNMC campus safety program and provide the only campus facilities for routine use of carcinogens and treatment of laboratory animals with carcinogens. The requirement to maintain our Safety Shared Resource was mandated by a CCSG site visit review team in 1994.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA036727-23
Application #
7484294
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2007-08-01
Budget End
2008-07-31
Support Year
23
Fiscal Year
2007
Total Cost
$24,752
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Kevadiya, Bhavesh D; Woldstad, Christopher; Ottemann, Brendan M et al. (2018) Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution. Theranostics 8:256-276
Wiest, Edwin J; Smith, Heather Jensen; Hollingsworth, Michael A (2018) Met receptor inhibitor SU11274 localizes in the endoplasmic reticulum. Biochem Biophys Res Commun 501:858-862
Leiphrakpam, Premila D; Brattain, Michael G; Black, Jennifer D et al. (2018) TGF? and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells. J Biol Chem 293:8242-8254
Uppada, Srijayaprakash Babu; Gowrikumar, Saiprasad; Ahmad, Rizwan et al. (2018) MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/?-catenin signaling. Mol Cancer 17:111
Won, Harim I; Schulze, Thomas T; Clement, Emalie J et al. (2018) De novo Assembly of the Burying Beetle Nicrophorus orbicollis (Coleoptera: Silphidae) Transcriptome Across Developmental Stages with Identification of Key Immune Transcripts. J Genomics 6:41-52
Zhou, Jiuli; Zeng, Yongji; Cui, Lian et al. (2018) Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activation. Proc Natl Acad Sci U S A 115:E6760-E6769
Das, Binita; Neilsen, Beth K; Fisher, Kurt W et al. (2018) A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells. Sci Rep 8:3770
Qazi, Asif Khurshid; Siddiqui, Jawed A; Jahan, Rahat et al. (2018) Emerging therapeutic potential of graviola and its constituents in cancers. Carcinogenesis 39:522-533
Hsu, Alice H; Lum, Michelle A; Shim, Kang-Sup et al. (2018) Crosstalk between PKC? and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium. Cell Rep 24:655-669
Svechkarev, Denis; Sadykov, Marat R; Bayles, Kenneth W et al. (2018) Ratiometric Fluorescent Sensor Array as a Versatile Tool for Bacterial Pathogen Identification and Analysis. ACS Sens 3:700-708

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