Abstract

The Safety Shared Resource is critical to the safe use of toxic agents in investigators' laboratories and in the Animal Care Shared Resource. The safety program in the UNMC/Eppley Cancer Center is based on general guidelines described in the """"""""National Cancer Institute Safety Standard for Research Involving Chemical Carcinogens"""""""" (NIH 76-900). These guidelines are supplemented by specific safety regulations prepared by the Safety Committee to govern the use of hazardous, toxic, carcinogenic, mixed waste and biohazardous materials. The policies and regulations of the Safety Shared Resource extend the UNMC campus safety program and provide the only campus facilities for routine use of carcinogens and treatment of laboratory animals with carcinogens. The requirement to maintain our Safety Shared Resource was mandated by a CCSG site visit review team in 1994.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA036727-23
Application #
7484294
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2007-08-01
Budget End
2008-07-31
Support Year
23
Fiscal Year
2007
Total Cost
$24,752
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Neilsen, Beth K; Chakraborty, Binita; McCall, Jamie L et al. (2018) WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage. BMC Cancer 18:673
Schopfer, Lawrence M; Lockridge, Oksana (2018) Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity. J Biol Chem 293:13566-13577
Baranovskiy, Andrey G; Duong, Vincent N; Babayeva, Nigar D et al. (2018) Activity and fidelity of human DNA polymerase ? depend on primer structure. J Biol Chem 293:6824-6843
Khadge, Saraswoti; Sharp, John Graham; Thiele, Geoffrey M et al. (2018) Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology. J Nutr Biochem 52:92-102
Kuss, Mitchell; Kim, Jiyoung; Qi, Dianjun et al. (2018) Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function. Acta Biomater 71:486-495
Ingersoll, Matthew A; Chou, Yu-Wei; Lin, Jamie S et al. (2018) p66Shc regulates migration of castration-resistant prostate cancer cells. Cell Signal 46:1-14
Svechkarev, Denis; Kyrychenko, Alexander; Payne, William M et al. (2018) Development of colloidally stable carbazole-based fluorescent nanoaggregates. J Photochem Photobiol A Chem 352:55-64
Ambardekar, Vishakha V; Wakaskar, Rajesh R; Ye, Zhen et al. (2018) Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration. Int J Pharm 543:130-138
Tian, Tian; Bi, Chengfeng; Hein, Ashley L et al. (2018) Rac1 is a novel therapeutic target in mantle cell lymphoma. Blood Cancer J 8:17
Saxena, Sugandha; Purohit, Abhilasha; Varney, Michelle L et al. (2018) Semaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells. BMC Cancer 18:1283

Showing the most recent 10 out of 1372 publications