Abstract

The goals of the Confocal Laser Scanning Microscope Shared Resource (CLSMSR) are to: (i) fill the need for high resolution image analysis of both live and fixed tissue and cultured cells; and (ii) provide the expertise needed both in preparing materials for microscopic examination and in carrying out image generation and analysis. The facility provides access to instrumentation, as well as the required technical and scientific expertise, and investigator training. The facility is directed by Dr. Judy Christman (Professor, Department of Biochemistry and Molecular Biology, UNMC). Cancer Center members with peer-reviewed funding account for more than 70% of the facility's usage

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA036727-23
Application #
7484304
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2007-08-01
Budget End
2008-07-31
Support Year
23
Fiscal Year
2007
Total Cost
$39,716
Indirect Cost

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Lockridge, Oksana; David, Emilie; Schopfer, Lawrence M et al. (2018) Purification of recombinant human butyrylcholinesterase on Hupresin®. J Chromatogr B Analyt Technol Biomed Life Sci 1102-1103:109-115
Saxena, Sugandha; Hayashi, Yuri; Wu, Lingyun et al. (2018) Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis. Oncotarget 9:5931-5943
Souza, Nathália P; Hard, Gordon C; Arnold, Lora L et al. (2018) Epithelium Lining Rat Renal Papilla: Nomenclature and Association with Chronic Progressive Nephropathy (CPN). Toxicol Pathol 46:266-272
Ray, Sutapa; Coulter, Don W; Gray, Shawn D et al. (2018) Suppression of STAT3 NH2 -terminal domain chemosensitizes medulloblastoma cells by activation of protein inhibitor of activated STAT3 via de-repression by microRNA-21. Mol Carcinog 57:536-548
Kanvinde, Shrey; Chhonker, Yashpal Singh; Ahmad, Rizwan et al. (2018) Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease. Acta Biomater 82:158-170
Payne, William M; Svechkarev, Denis; Kyrychenko, Alexander et al. (2018) The role of hydrophobic modification on hyaluronic acid dynamics and self-assembly. Carbohydr Polym 182:132-141
Sanchez, Sonia M Rocha; Fuson, Olivia; Tarang, Shikha et al. (2018) Quinoxaline protects zebrafish lateral line hair cells from cisplatin and aminoglycosides damage. Sci Rep 8:15119
Stepchenkova, E I; Shiriaeva, A A; Pavlov, Y I (2018) Deletion of the DEF1 gene does not confer UV-immutability but frequently leads to self-diploidization in yeast Saccharomyces cerevisiae. DNA Repair (Amst) 70:49-54
Wang, Zhan; Chen, Xingcheng; Zhong, Mei-Zuo et al. (2018) Cyclin-dependent kinase 1-mediated phosphorylation of YES links mitotic arrest and apoptosis during antitubulin chemotherapy. Cell Signal 52:137-146
Svechkarev, Denis; Kyrychenko, Alexander; Payne, William M et al. (2018) Probing the self-assembly dynamics and internal structure of amphiphilic hyaluronic acid conjugates by fluorescence spectroscopy and molecular dynamics simulations. Soft Matter 14:4762-4771

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