Abstract

The Confocal Shared Laser Scanning Microscope Facility (CLSMF) has been active on the UNMC campus since 1996 when it was established through institutional funding. The objectives of the CLSMF are as follows: 1. To fill the need for high resolution image analysis of both live and fixed tissue and cultured cells. 2. To provide training in the use of analysis tools for live cell component analysis of FRET, FRAP and FLIP experiments. 3. To provide essential hard and software for analysis of collected data. 4. To provide the expertise needed both in preparing materials for microscopic examination and in carrying out image generation and analysis

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA036727-26
Application #
8555639
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-09-05
Project End
2016-07-31
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
26
Fiscal Year
2012
Total Cost
$22,135
Indirect Cost
$7,605

  Institution

Name
University of Nebraska Medical Center
Department
Type
DUNS #
168559177
City
Omaha
State
NE
Country
United States
Zip Code
68198

  Publications

Neilsen, Beth K; Chakraborty, Binita; McCall, Jamie L et al. (2018) WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage. BMC Cancer 18:673
Schopfer, Lawrence M; Lockridge, Oksana (2018) Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity. J Biol Chem 293:13566-13577
Baranovskiy, Andrey G; Duong, Vincent N; Babayeva, Nigar D et al. (2018) Activity and fidelity of human DNA polymerase ? depend on primer structure. J Biol Chem 293:6824-6843
Khadge, Saraswoti; Sharp, John Graham; Thiele, Geoffrey M et al. (2018) Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology. J Nutr Biochem 52:92-102
Kuss, Mitchell; Kim, Jiyoung; Qi, Dianjun et al. (2018) Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function. Acta Biomater 71:486-495
Ingersoll, Matthew A; Chou, Yu-Wei; Lin, Jamie S et al. (2018) p66Shc regulates migration of castration-resistant prostate cancer cells. Cell Signal 46:1-14
Svechkarev, Denis; Kyrychenko, Alexander; Payne, William M et al. (2018) Development of colloidally stable carbazole-based fluorescent nanoaggregates. J Photochem Photobiol A Chem 352:55-64
Ambardekar, Vishakha V; Wakaskar, Rajesh R; Ye, Zhen et al. (2018) Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration. Int J Pharm 543:130-138
Tian, Tian; Bi, Chengfeng; Hein, Ashley L et al. (2018) Rac1 is a novel therapeutic target in mantle cell lymphoma. Blood Cancer J 8:17
Saxena, Sugandha; Purohit, Abhilasha; Varney, Michelle L et al. (2018) Semaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells. BMC Cancer 18:1283

Showing the most recent 10 out of 1372 publications