Abstract

The Tissue Procurement Shared Resource provides investigators at the University of Utah with optimally preserved tissues and cells from human subjects who have given their informed consent to participate in cancer research. Our centralized shared resource relieves many investigators from the need to prepare protocols and seek IRB approval to collect tissue and cells. It also reduces the burden placed on patients to evaluate and grant informed consent. Consented subjects are also asked for permission to link their tissue and cell specimens to medical information and authorization to use protected health information to improve study design and data interpretation. Confidentiality is provided by assignment of unique identifiers and award of a Confidentiality Certificate from NCI. Collected tissue and cell specimens are divided into fresh, frozen and fixed samples. Distribution is to investigators who follow a procedure that facilitates tracking of the samples. The outcome has been centralized procurement, storage, and distribution of tissues and cells for cancer research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA042014-17
Application #
6990232
Study Section
Subcommittee G - Education (NCI)
Project Start
2004-07-09
Project End
2006-04-30
Budget Start
2004-07-09
Budget End
2005-04-30
Support Year
17
Fiscal Year
2004
Total Cost
$10,449
Indirect Cost

  Institution

Name
University of Utah
Department
Type
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Piñas, Germán E; DeSantis, Michael D; Parkinson, John S (2018) Noncritical Signaling Role of a Kinase-Receptor Interaction Surface in the Escherichia coli Chemosensory Core Complex. J Mol Biol 430:1051-1064
Sadler, Jessica B A; Wenzel, Dawn M; Williams, Lauren K et al. (2018) A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability. Proc Natl Acad Sci U S A 115:E8900-E8908
Stump, Tammy K; Aspinwall, Lisa G; Kohlmann, Wendy et al. (2018) Genetic Test Reporting and Counseling for Melanoma Risk in Minors May Improve Sun Protection Without Inducing Distress. J Genet Couns 27:955-967
Rambau, Peter F; Vierkant, Robert A; Intermaggio, Maria P et al. (2018) Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study. J Pathol Clin Res 4:250-261
Tavtigian, Sean V; Greenblatt, Marc S; Harrison, Steven M et al. (2018) Modeling the ACMG/AMP variant classification guidelines as a Bayesian classification framework. Genet Med 20:1054-1060
Rogers, R Aaron; Fleming, Aaron M; Burrows, Cynthia J (2018) Unusual Isothermal Hysteresis in DNA i-Motif pH Transitions: A Study of the RAD17 Promoter Sequence. Biophys J 114:1804-1815
Rogers, R Aaron; Fleming, Aaron M; Burrows, Cynthia J (2018) Rapid Screen of Potential i-Motif Forming Sequences in DNA Repair Gene Promoters. ACS Omega 3:9630-9635
Wei, Xiaomu; Calvo-Vidal, M Nieves; Chen, Siwei et al. (2018) Germline Lysine-Specific Demethylase 1 (LSD1/KDM1A) Mutations Confer Susceptibility to Multiple Myeloma. Cancer Res 78:2747-2759
Sample, Danielle C; Samadder, N Jewel; Pappas, Lisa M et al. (2018) Variables affecting penetrance of gastric and duodenal phenotype in familial adenomatous polyposis patients. BMC Gastroenterol 18:115
Barrott, Jared J; Illum, Benjamin E; Jin, Huifeng et al. (2018) Paracrine osteoprotegerin and ?-catenin stabilization support synovial sarcomagenesis in periosteal cells. J Clin Invest 128:207-218

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