The Case Western Reserve University/Ireland Cancer Center is a multi- disciplinary, clinical, and laboratory research center, combining the resources and expertise at Case Western Reserve University and University Hospitals of Cleveland, with the participation of two major affiliate hospitals-MetroHealth Medical Center and the Cleveland Department of Veterans Affairs Medical Center. The Cancer Center program spans 29 departments in the Schools of Medicine, Nursing, Engineering, and the College of Arts and Sciences at Case Western Reserve University. The objectives of the Case Western Reserve University/Ireland Cancer Center are: 1) to improve the prevention, diagnosis, and therapy of cancer through research; 2) to stimulate and support innovative, coordinated, interdisciplinary research on cancer diagnosis, treatment, and control; 3) to develop clinical applications of research discoveries and to make these applications available to Northeast Ohio residents as quickly as possible; and 4) to develop cancer prevention and control activities that most effectively utilize the clinical and laboratory expertise at Case Western Reserve University and contribute to the reduction of cancer morbidity and mortality in Northeast Ohio and the surrounding region. The goals of the center are accomplished by activities in six active programs (Molecular Biology of Oncogenesis, Molecular Virology, Cancer Genetics, Radiation Biology, Hematopoietic and Immune Cell Biology, and Developmental Therapeutics); one developing program (Cancer Prevention and Control); and ten shared resources (Molecular Biology, Flow Cytometry, Radiation Resources, Media Preparation, Histology, Athymic Animal, Hematopoietic Stem Cell, Clinical Pharmacology, Biostatistics/Epidemiology, and Clinical Trials.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA043703-12
Application #
6172548
Study Section
Cancer Centers and Research Programs Review Committee (CCRP)
Program Officer
Silkensen, Shannon M
Project Start
1991-09-30
Project End
2001-07-31
Budget Start
2000-08-25
Budget End
2001-07-31
Support Year
12
Fiscal Year
2000
Total Cost
$1,858,039
Indirect Cost
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Somasegar, Sahana; Li, Li; Thompson, Cheryl L (2018) No association of reproductive risk factors with breast cancer tumor grade. Eur J Cancer Prev 27:140-143
Gu, Xiaorong; Ebrahem, Quteba; Mahfouz, Reda Z et al. (2018) Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates. J Clin Invest 128:4260-4279
Bosca, Federica; Bielecki, Peter A; Exner, Agata A et al. (2018) Porphyrin-Loaded Pluronic Nanobubbles: A New US-Activated Agent for Future Theranostic Applications. Bioconjug Chem 29:234-240
Benson, Bryan L; Li, Lucy; Myers, Jay T et al. (2018) Biomimetic post-capillary venule expansions for leukocyte adhesion studies. Sci Rep 8:9328
Morrow, James J; Bayles, Ian; Funnell, Alister P W et al. (2018) Positively selected enhancer elements endow osteosarcoma cells with metastatic competence. Nat Med 24:176-185
Cooper, Gregory S; Markowitz, Sanford D; Chen, Zhengyi et al. (2018) Evaluation of Patients with an Apparent False Positive Stool DNA Test: The Role of Repeat Stool DNA Testing. Dig Dis Sci 63:1449-1453
Burger, Denis R; Parker, Yvonne; Guinta, Kathryn et al. (2018) PRO 140 Monoclonal Antibody to CCR5 Prevents Acute Xenogeneic Graft-versus-Host Disease in NOD-scid IL-2Rynull Mice. Biol Blood Marrow Transplant 24:260-266
Anderson, Christian E; Wang, Charlie Y; Gu, Yuning et al. (2018) Regularly incremented phase encoding - MR fingerprinting (RIPE-MRF) for enhanced motion artifact suppression in preclinical cartesian MR fingerprinting. Magn Reson Med 79:2176-2182
Tartakoff, Alan Michael; Dulce, David; Landis, Elizabeth (2018) Delayed Encounter of Parental Genomes Can Lead to Aneuploidy in Saccharomyces cerevisiae. Genetics 208:139-151
Shi, Xiaojun; Wang, Bingcheng (2018) Caught in the ""Akt"": Cross-talk between EphA2 and EGFR through the Akt-PIKfyve axis maintains cellular sensitivity to EGF. Sci Signal 11:

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