Abstract

Development Funds Development Funds support the recruitment of new investigators, innovative collaborative research focusing on translational research efforts and the development of new shared core facilities. In the past, these funds have been effectively utilized and leveraged with institutional funds. The success of these efforts is demonstrated by the high success rate of newly recruited investigators in obtaining peer reviewed funding; by the success of the recipients of pilot collaborative awards at receiving multi-investigator peer reviewed research funding, and by the success of establishing new cores and improving the function of existing cores. Twenty six of the twenty eight recipients of NCI development funds over this grant period have peer reviewed funding. Five of the six innovation grants awarded have yielded either a P01, Center grant or multi-investigator R01, with another center grant pending. Core investments have contributed to three new cores. NCI development funds have yielded a strong return in investment over this grant period. With the continued expansion of research and clinical space, including the opening of new research facilities in 2006, the Cancer Center is in excellent position to leverage core grant development funds in the future to capitalize on new scientific opportunities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA046592-23
Application #
8147777
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
23
Fiscal Year
2010
Total Cost
$868,039
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Feng, Mary; Suresh, Krithika; Schipper, Matthew J et al. (2018) Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors in Patients at High Risk for Liver Damage: A Phase 2 Clinical Trial. JAMA Oncol 4:40-47
Xiong, Yi; Torsoni, Adriana Souza; Wu, Feihua et al. (2018) Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases. Elife 7:
El Kadi, Najwa; Wang, Luo; Davis, April et al. (2018) The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer. Cancer Res 78:6728-6735
Namkoong, Sim; Ho, Allison; Woo, Yu Mi et al. (2018) Systematic Characterization of Stress-Induced RNA Granulation. Mol Cell 70:175-187.e8
Thomas, Tina T; Chukkapalli, Sahiti; Van Noord, Raelene A et al. (2018) Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts. J Vis Exp :
Eisenberg, Marisa C; Campredon, Lora P; Brouwer, Andrew F et al. (2018) Dynamics and Determinants of HPV Infection: The Michigan HPV and Oropharyngeal Cancer (M-HOC) Study. BMJ Open 8:e021618
Boonstra, Philip S; Barbaro, Ryan P (2018) Incorporating historical models with adaptive Bayesian updates. Biostatistics :
Johnson, Allison M; Roach, James P; Hu, Anna et al. (2018) Connexin 43 gap junctions contribute to brain endothelial barrier hyperpermeability in familial cerebral cavernous malformations type III by modulating tight junction structure. FASEB J 32:2615-2629
Feinberg, Tamar Y; Zheng, Huarui; Liu, Rui et al. (2018) Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs. Dev Cell 47:145-160.e6
Hrycaj, Steven M; Marty-Santos, Leilani; Cebrian, Cristina et al. (2018) Hox5 genes direct elastin network formation during alveologenesis by regulating myofibroblast adhesion. Proc Natl Acad Sci U S A 115:E10605-E10614

Showing the most recent 10 out of 1493 publications