The Shared Computer Facility is an essential and important computer resource both for basic science and clinical research at the Kimmel Cancer Center, providing shared computer hardware and software infrastructure, software development, and consultative services for computer-related concerns. In support of basic science at KCC, this is the primary Facility for scientist support with DNA/Amino Acid Sequence Analysis, and is a computational resource for the Structural Biology group which includes molecular modeling, NMR and x-ray crystallography. The Shared Computer Facility also support clinical research, providing computer resources for the Clinical Trial Support Services, the Jefferson Cancer Network, various program projects, and individual clinical researchers. Applications have been developed to provide controlled and secure access to clinical data, laboratory data, and protocol information for research and the management of clinical trials. For both KCC basic scientists and clinicians, the Shared Computer Facility provides the basic computing infrastructure, including network-accessible mass (disk) storage, Internet/World-Wide-Web access, and hardware and software experience. The SCF staff works closely with the University's information systems and hardware and software expertise. The SCF staff works closely with the University's information systems department, supplementing the generic network support provided by TJU with more comprehensive services attuned to the specific needs of cancer research. Additionally, SCF staff are available to KCC members for consultation on computer specifications and purchases, hardware and software installation and configuration, applications use, and trouble-shooting computer use problems.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA056036-05
Application #
6658322
Study Section
Project Start
2002-06-01
Project End
2003-05-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
5
Fiscal Year
2002
Total Cost
$279,549
Indirect Cost
Name
Thomas Jefferson University
Department
Type
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Liao, Lili; Liu, Zongzhi Z; Langbein, Lauren et al. (2018) Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer. Elife 7:
Heeke, Arielle L; Pishvaian, Michael J; Lynce, Filipa et al. (2018) Prevalence of Homologous Recombination-Related Gene Mutations Across Multiple Cancer Types. JCO Precis Oncol 2018:
Parent, Kristin N; Schrad, Jason R; Cingolani, Gino (2018) Breaking Symmetry in Viral Icosahedral Capsids as Seen through the Lenses of X-ray Crystallography and Cryo-Electron Microscopy. Viruses 10:
Rappaport, Jeffrey A; Waldman, Scott A (2018) The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. Front Oncol 8:299
Pandya, Kalgi D; Palomo-Caturla, Isabel; Walker, Justin A et al. (2018) An Unmutated IgM Response to the Vi Polysaccharide of Salmonella Typhi Contributes to Protective Immunity in a Murine Model of Typhoid. J Immunol 200:4078-4084
Hussain, Maha; Daignault-Newton, Stephanie; Twardowski, Przemyslaw W et al. (2018) Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012. J Clin Oncol 36:991-999
Shafi, Ayesha A; Schiewer, Matthew J; de Leeuw, Renée et al. (2018) Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response. Eur Urol Oncol 1:325-337
Meyer, Sara E; Muench, David E; Rogers, Andrew M et al. (2018) miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential. J Exp Med 215:2115-2136
Mazina, Olga M; Mazin, Alexander V (2018) Reconstituting the 4-Strand DNA Strand Exchange. Methods Enzymol 600:285-305
Magee, Michael S; Abraham, Tara S; Baybutt, Trevor R et al. (2018) Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases. Cancer Immunol Res 6:509-516

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