TRANSLATIONAL RESEARCH SHARED RESOURCESince the inception of the Translational Research Shared Resource (formerly the 'Pathology Core') itsmission has been to provide tissue processing, slide preparation, histochemical staining andimmunohistochemical staining for human neoplastic tissue and experimental animal model tissue beingutilized by KCC researchers. This shared resource has also provided procurement, banking and distributionof human neoplastic tissue in order to facilitate translational research. The recently instituted caBIG clinicaldata base provides pathologic and clinical information corresponding to the tissue specimens present in theresource tumor/tissue bank. In addition, the Translational Research Shared Resource provides tissuemicroarrays using standard and CEMA technology with paraffin archive material from the resourcetumor/tissue bank. Laser microdissection of distinct cell and tissue types for molecular analysis can beperformed on the resource's Laser Microdissection system. For all of the capabilities offered by theTranslational Research Shared Resource, staff is available to provide technical support and pathologyexpertise to KCC investigators. In 2006 twenty nine principal investigators from various programs of KCCincluding Cancer Cell Biology & Signaling, Molecular Biology & Genetics, Immunological Mechanisms inCancer, Endocrine Mechanisms & Hormone Action in Cancer, Radiation Research & Translational Biologyand Gastrointestinal Cancer benefited from this shared resource.
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