Abstract

CANCER CENTER FACILITIES The Kimmel Cancer Center is located on the campus of Thomas Jefferson University (TJU) and is part of Jefferson Medical College, founded in 1824. Jefferson Medical College is one of the largest private medical schools in the nation and is located in Center City Philadelphia (Fig. 3). The facilities strategic plan of TJU and TJUH has been developed. The KCC and its facilities are a centerpiece of the campus. The Biostatistical and Administrative offices of the Radiation Therapy Oncology Group (RTOG) are located a few blocks from KCC. as are the headquarters of the Coalition of Cancer Cooperative Groups (CCCG). The RTOG Translational Research Program Committee is co-chaired by Dr. Dicker, leader of the KCC's RRTB program. Dr. Comis, a new KCC Member, who is a faculty member of Drexel University, is the President and CEO of the CCCG and Group Chair of the Eastern Cooperative Oncology Group (ECOG). (Drexel University has a medical school and hospital campus in addition to strengths in biomedical engineering). Philadelphia has four medical schools and four NCI-designated Cancer Centers (University of Pennsylvania, Wistar Institute, Fox Chase Cancer Center and Kimmel Cancer Center). The Cancer Centers at Penn and Wistar are, approximately 20 blocks away from the KCC on the west side of the Schuylkill River. Because of this small distance, Penn and Wistar investigators often attend KCC seminars and functions and vice versa.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
4P30CA056036-17
Application #
9071344
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
2016-06-01
Project End
2018-05-31
Budget Start
2016-06-01
Budget End
2017-05-31
Support Year
17
Fiscal Year
2016
Total Cost
Indirect Cost

  Institution

Name
Thomas Jefferson University
Department
Type
DUNS #
053284659
City
Philadelphia
State
PA
Country
United States
Zip Code
19107

  Publications

Magee, Michael S; Abraham, Tara S; Baybutt, Trevor R et al. (2018) Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases. Cancer Immunol Res 6:509-516
Chervoneva, Inna; Freydin, Boris; Hyslop, Terry et al. (2018) Modeling qRT-PCR dynamics with application to cancer biomarker quantification. Stat Methods Med Res 27:2581-2595
Capparelli, Claudia; Purwin, Timothy J; Heilman, Shea A et al. (2018) ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma. Cancer Res 78:5680-5693
Nevler, Avinoam; Muller, Alexander J; Cozzitorto, Joseph A et al. (2018) A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2. J Am Coll Surg 226:596-603
Peng, Weidan; Furuuchi, Narumi; Aslanukova, Ludmila et al. (2018) Elevated HuR in Pancreas Promotes a Pancreatitis-Like Inflammatory Microenvironment That Facilitates Tumor Development. Mol Cell Biol 38:
Waldman, Scott A; Camilleri, Michael (2018) Guanylate cyclase-C as a therapeutic target in gastrointestinal disorders. Gut 67:1543-1552
Sullivan-Reed, Katherine; Bolton-Gillespie, Elisabeth; Dasgupta, Yashodhara et al. (2018) Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells. Cell Rep 23:3127-3136
Lu, Huimin; Bowler, Nicholas; Harshyne, Larry A et al. (2018) Exosomal ?v?6 integrin is required for monocyte M2 polarization in prostate cancer. Matrix Biol 70:20-35
Lapadula, Dominic; Farias, Eduardo; Randolph, Clinita E et al. (2018) Effects of Oncogenic G?q and G?11 Inhibition by FR900359 in Uveal Melanoma. Mol Cancer Res :
Vite, Alexia; Zhang, Caimei; Yi, Roslyn et al. (2018) ?-Catenin-dependent cytoskeletal tension controls Yap activity in the heart. Development 145:

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