The Robert H. Lurie Comprehensive Cancer Center of Northwestern University is an NCI-designated, university-based, matrix cancer center conducting a broad range of multidisciplinary clinical, laboratory and population science research. The Cancer Center integrates the expertise and resources of the Medical School (Chicago Campus) and its five affiliated hospitals along with those of departments located on the University?s Evanston Campus. Established in 1974, the Cancer Center functions as a full organizational unit with the status of a department of the Medical School. Since its inception, the Cancer Center has been dedicated to the process of discovery, advancing medical knowledge and providing compassionate, state-of-the-art cancer care, as reflected in the following goals: 1. To conduct and support cancer research and to integrate cancer-related research throughout the University 2. To coordinate and integrate cancer-related activities of the University including community outreach initiatives 3. To develop and conduct cancer education programs 4. To promote and participate in state-of-the-art care of cancer patients at the affiliated hospitals of the McGaw Medical Center of Northwestern University, and 5. To develop and implement initiatives in cancer prevention and control research 6. These goals are accomplished through the activities of 10 established programs and 13 shared resources. Programs: Viral Oncogenesis, Tumor Invasion, Metastasis, & Angiogenesis, Hormone Action/Signal Transduction in Cancer, Cancer Genes and Molecular Regulation, Breast Cancer, Prostate Cancer, Hematologic Malignancies, Pediatric Oncology, Cancer Prevention, and Cancer Control. Shared Resources: Media Prep, Flow Cytometry, Cell Imaging, Transgenic Core, Pathology Core, Biotechnology, Keck Biophysics, Monoclonal Antibodies, Immunoassay, MR Research, Structural Biology, Biostatistics Core, and Clinical Research Office.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
3P30CA060553-13S4
Application #
7283347
Study Section
Subcommittee G - Education (NCI)
Program Officer
Ogunbiyi, Peter
Project Start
1993-08-01
Project End
2007-07-31
Budget Start
2005-08-01
Budget End
2007-07-31
Support Year
13
Fiscal Year
2006
Total Cost
$207,340
Indirect Cost
Name
Northwestern University at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Fisher, Daniel W; Han, Ye; Lyman, Kyle A et al. (2018) HCN channels in the hippocampus regulate active coping behavior. J Neurochem 146:753-766
Sullivan, David P; Bui, Triet; Muller, William A et al. (2018) In vivo imaging reveals unique neutrophil transendothelial migration patterns in inflamed intestines. Mucosal Immunol 11:1571-1581
Russi, Abigail E; Ebel, Mark E; Yang, Yuchen et al. (2018) Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility. Proc Natl Acad Sci U S A 115:E1520-E1529
Frankowski, Kevin J; Wang, Chen; Patnaik, Samarjit et al. (2018) Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med 10:
Melo-Cardenas, Johanna; Xu, Yuanming; Wei, Juncheng et al. (2018) USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism. Blood 132:423-434
Sato, Tatsuya; Chang, Hsiang-Chun; Bayeva, Marina et al. (2018) mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function. Proc Natl Acad Sci U S A 115:E6291-E6300
Wiwatpanit, Teerawat; Lorenzen, Sarah M; Cantú, Jorge A et al. (2018) Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature 563:691-695
Spring, Bonnie; Pellegrini, Christine; McFadden, H G et al. (2018) Multicomponent mHealth Intervention for Large, Sustained Change in Multiple Diet and Activity Risk Behaviors: The Make Better Choices 2 Randomized Controlled Trial. J Med Internet Res 20:e10528
Buglak, Nicholas E; Jiang, Wulin; Bahnson, Edward S M (2018) Cinnamic aldehyde inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in Zucker Diabetic Fatty rats. Redox Biol 19:166-178
Yang, Ruiguo; Lemaître, Vincent; Huang, Changjin et al. (2018) Monoclonal Cell Line Generation and CRISPR/Cas9 Manipulation via Single-Cell Electroporation. Small 14:e1702495

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