The Biostatistics Shared Resource (BSR) assists clinical, epidemiologic, and basic science investigators within the Cancer Center with study design, dat analysis, and linkage of clinical, epidemiologic, and laboratory data. The BSR plays an active role in the design of new studies with a concentration in cancer etiology, genetics, detection, and prevention. Major emphasis is placed on developing and maintaining statistical quality control procedures. The Shared Resource provides linkage of laboratory tumor data, clinical information, demographic information, and follow-up data. Statistical consultations involve participation in the design of the research, quantitative description of the protocol, calculation of sample size requirements, and description of statistical methods. Since 1998, the Biostatistics Shared Resource has devoted 36% of service to peer-reviewed funded projects, 29% to educational efforts and development of statistical resources, 11% to peer-reviewed funded projects, 29% to educational efforts and development of statistical resources, 11% to peer-reviewed agency submissions, 10% to project development, 10% to CTPRMC-approved clinical trials, and 4% of service to non-Cancer Center usage. Assistance has been provided to Cancer Center investigators in the following programs: Clinical Oncology, Epidemiology, Carcinogenesis, Photomedicine, Growth Factors and Signaling, Structural Molecular Biology, and Virology. In summary, the Biostatistics Shared Resource has continued to contribute heavily to research efforts at the Chao Family Comprehensive Cancer Center.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA062203-09
Application #
6660919
Study Section
Project Start
2002-09-19
Project End
2003-02-28
Budget Start
Budget End
Support Year
9
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Type
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Konstorum, Anna; Lowengrub, John S (2018) Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model. J Theor Biol 439:86-99
Yan, Huaming; Konstorum, Anna; Lowengrub, John S (2018) Three-Dimensional Spatiotemporal Modeling of Colon Cancer Organoids Reveals that Multimodal Control of Stem Cell Self-Renewal is a Critical Determinant of Size and Shape in Early Stages of Tumor Growth. Bull Math Biol 80:1404-1433
Wang, Xiaolin; Zhao, Da; Phan, Duc T T et al. (2018) A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function. Lab Chip 18:2167-2177
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Reidling, Jack C; Relaño-Ginés, Aroa; Holley, Sandra M et al. (2018) Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice. Stem Cell Reports 10:58-72
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Santos, Rommel A; Fuertes, Ariel J C; Short, Ginger et al. (2018) DSCAM differentially modulates pre- and postsynaptic structural and functional central connectivity during visual system wiring. Neural Dev 13:22
Ullmer, Wendy; Semler, Bert L (2018) Direct and Indirect Effects on Viral Translation and RNA Replication Are Required for AUF1 Restriction of Enterovirus Infections in Human Cells. MBio 9:

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