Abstract

The Biobehavioral Shared Resource was established to assist cancer researchers efforts through measurement of patient-reported outcomes across Cancer Center Programs.
The aim of the Biobehavioral Shared Resource is to support cancer researchers by providing them with the necessary expertise and assistance to incorporate patient/participant-reported outcomes into their projects. During this five-year period (2002-2007) as a developing Shared Resource, we have collaborated with 37 investigators, spanning six Cancer Center programs, to participate in over $10 million of funded research. The Biobehavioral Shared Resource has contributed to 50 publications, and has experienced steady growth in number of users and diversity of projects. Current services and support include: Patient-reported outcome (PRO) Instrument Selection, PRO Instrument Development, Research Design Considerations, Data Collection Strategies, and Results Interpretation. Expansion of these services will include IRB assistance to integrate PROs into grant applications, provide PRO data management, develop an electronic library of PRO measures, and integrate the NIH PROMIS initiative into key clinical trials. The Biobehavioral Shared Resource has been supported by the Cancer Center as a developing Shared Resource for the past three years. Permanent funds are now requested for support as a full Shared Resource.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA062203-16
Application #
8215296
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2011-02-01
Budget End
2012-01-31
Support Year
16
Fiscal Year
2011
Total Cost
$56,894
Indirect Cost

  Institution

Name
University of California Irvine
Department
Type
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697

  Publications

Koay, Eugene J; Lee, Yeonju; Cristini, Vittorio et al. (2018) A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma. Clin Cancer Res 24:5883-5894
Wilford, Justin; Osann, Kathryn; Hsieh, Susie et al. (2018) Validation of PROMIS emotional distress short form scales for cervical cancer. Gynecol Oncol 151:111-116
Bagaev, Alexander; Pichugin, Aleksey; Nelson, Edward L et al. (2018) Anticancer Mechanisms in Two Murine Bone Marrow-Derived Dendritic Cell Subsets Activated with TLR4 Agonists. J Immunol 200:2656-2669
Gong, Nian; Park, John; Luo, Z David (2018) Injury-induced maladaptation and dysregulation of calcium channel ?2 ? subunit proteins and its contribution to neuropathic pain development. Br J Pharmacol 175:2231-2243
Qiu, Xiaolong; Huang, Jen-Huang; Westerhof, Trisha M et al. (2018) Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue. Sci Rep 8:2774
Kim, Seong M; Nguyen, Tricia T; Ravi, Archna et al. (2018) PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells. Cancer Discov 8:866-883
Zhu, Yong; Wang, Xiuye; Forouzmand, Elmira et al. (2018) Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation. Mol Cell 69:62-74.e4
Mishra, Birendra; Lawson, Gregory W; Ripperdan, Ryan et al. (2018) Charged-Iron-Particles Found in Galactic Cosmic Rays are Potent Inducers of Epithelial Ovarian Tumors. Radiat Res 190:142-150
Song, Wan; Zsindely, Nóra; Faragó, Anikó et al. (2018) Systematic genetic interaction studies identify histone demethylase Utx as potential target for ameliorating Huntington's disease. Hum Mol Genet 27:649-666
Lin, Xiaoxiao; Itoga, Christy A; Taha, Sharif et al. (2018) c-Fos mapping of brain regions activated by multi-modal and electric foot shock stress. Neurobiol Stress 8:92-102

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