The overarching goal of the Biostatistics Shared Resource (BSR) within the Chao Family ComprehensiveCancer Center (CFCCC) is to provide statistical and intellectual support to all CFCCC investigators at allphases of scientific projects. The mission of the BSR faculty and staff is to be intimately involved in theconception, design, implementation, analysis, and reporting of research conducted by members of the CFCCC.While the majority of effort from BSR faculty is devoted to providing collaboration and service to CFCCCinvestigators the BSR also encourages the development of statistical methodologic research that relatesdirectly to the scientific agenda and needs of CFCCC investigators. The BSR is staffed by six PhD levelstatisticians and one MS level statistician. Dr. Daniel Gillen, Professor of Statistics with affiliate appointments inthe Department of Epidemiology and the Program in Public Health, serves as the Director of the BSR. Dr.Michael Phelan serves as the BSR Facilities Manager. Drs. Christine McLaren, Kathryn Osann, ThomasTaylor, and Chad Garner all hold faculty appointments at UC Irvine. The faculty and staff of the BSR haveparticular expertise in multiple areas of statistical methodology with applications to cancer research, makingthem an invaluable resource for CFCCC members and key contributors to the overall research mission of theCancer Center. Examples of the many services provided by the BSR include collaboration on study design,data analysis, and interpretation, development of research protocols and grant proposals, assistance withdatabase design and linkage of clinical, epidemiologic, and laboratory data, statistical expertise for CFCCCoversight committees, and education, training, and mentoring of CFCCC members.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA062203-20
Application #
9208761
Study Section
Subcommittee A - Cancer Centers (NCI-A)
Project Start
Project End
Budget Start
2017-02-01
Budget End
2018-01-31
Support Year
20
Fiscal Year
2017
Total Cost
$65,745
Indirect Cost
$23,192
Name
University of California Irvine
Department
Type
Domestic Higher Education
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92617
Sierra, Robert A; Hoverter, Nathan P; Ramirez, Ricardo N et al. (2018) TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency. Development 145:
Maciejewski, Sonia; Ullmer, Wendy; Semler, Bert L (2018) VPg unlinkase/TDP2 in cardiovirus infected cells: Re-localization and proteolytic cleavage. Virology 516:139-146
Konstorum, Anna; Lowengrub, John S (2018) Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model. J Theor Biol 439:86-99
Yan, Huaming; Konstorum, Anna; Lowengrub, John S (2018) Three-Dimensional Spatiotemporal Modeling of Colon Cancer Organoids Reveals that Multimodal Control of Stem Cell Self-Renewal is a Critical Determinant of Size and Shape in Early Stages of Tumor Growth. Bull Math Biol 80:1404-1433
Wang, Xiaolin; Zhao, Da; Phan, Duc T T et al. (2018) A hydrostatic pressure-driven passive micropump enhanced with siphon-based autofill function. Lab Chip 18:2167-2177
Flather, Dylan; Nguyen, Joseph H C; Semler, Bert L et al. (2018) Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virus. PLoS Pathog 14:e1007277
Hou, Jue; Williams, Joshua; Botvinick, Elliot L et al. (2018) Visualization of Breast Cancer Metabolism Using Multimodal Nonlinear Optical Microscopy of Cellular Lipids and Redox State. Cancer Res 78:2503-2512
George, Andrée S; Cox, Clayton E; Desai, Prerak et al. (2018) Interactions of Salmonella enterica Serovar Typhimurium and Pectobacterium carotovorum within a Tomato Soft Rot. Appl Environ Microbiol 84:
Reidling, Jack C; Relaño-Ginés, Aroa; Holley, Sandra M et al. (2018) Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice. Stem Cell Reports 10:58-72
Lagarrigue, Frederic; Gingras, Alexandre R; Paul, David S et al. (2018) Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation. Blood Adv 2:2358-2368

Showing the most recent 10 out of 1106 publications