Abstract

The Peptide Sequencing and Amino Acid Analysis Shared Resource provides essentially four different services that include the analyses of N-terminal amino acid sequence, internal sequence and amino acid composition and the purification of peptides. Since September 1995, when the Cancer Center Support Grant was funded, this resource has served 38 different Cancer Center investigators (of a total of 74 investigators at Vanderbilt University). Over 317 samples have been analyzed for their peptide sequences and 402 amino acid compositions have been determined within the same time period. The overall usage by the Cancer Center investigators accounts for approximately 57.4 percent of the entire usage. This Resource will continue to provide the four existing services to meet the demand for the identification of peptides and for acquiring the basic knowledge of the structural information of peptides.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA068485-05
Application #
6398646
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
2000-09-01
Project End
2001-08-31
Budget Start
Budget End
Support Year
5
Fiscal Year
2000
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37203

  Publications

Takata, Yumie; Xiang, Yong-Bing; Burk, Raymond F et al. (2018) Plasma selenoprotein P concentration and lung cancer risk: results from a case-control study nested within the Shanghai Men's Health Study. Carcinogenesis 39:1352-1358
Feng, Yinnian; Reinherz, Ellis L; Lang, Matthew J (2018) ?? T Cell Receptor Mechanosensing Forces out Serial Engagement. Trends Immunol 39:596-609
Sucre, Jennifer M S; Deutsch, Gail H; Jetter, Christopher S et al. (2018) A Shared Pattern of ?-Catenin Activation in Bronchopulmonary Dysplasia and Idiopathic Pulmonary Fibrosis. Am J Pathol 188:853-862
Rogers, Meredith C; Lamens, Kristina D; Shafagati, Nazly et al. (2018) CD4+ Regulatory T Cells Exert Differential Functions during Early and Late Stages of the Immune Response to Respiratory Viruses. J Immunol 201:1253-1266
Rosenberg, Adam J; Nickels, Michael L; Schulte, Michael L et al. (2018) Automated radiosynthesis of 5-[11C]l-glutamine, an important tracer for glutamine utilization. Nucl Med Biol 67:10-14
Dean, Donnatesa A L; Griffith, Derek M; McKissic, Sydika A et al. (2018) Men on the Move-Nashville: Feasibility and Acceptability of a Technology-Enhanced Physical Activity Pilot Intervention for Overweight and Obese Middle and Older Age African American Men. Am J Mens Health 12:798-811
Choi, Eunyoung; Lantz, Tyler L; Vlacich, Gregory et al. (2018) Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach. Gut 67:1595-1605
Parl, Fritz F; Crooke, Philip S; Plummer Jr, W Dale et al. (2018) Genomic-Epidemiologic Evidence That Estrogens Promote Breast Cancer Development. Cancer Epidemiol Biomarkers Prev 27:899-907
Marks, Christian R; Shonesy, Brian C; Wang, Xiaohan et al. (2018) Activated CaMKII? Binds to the mGlu5 Metabotropic Glutamate Receptor and Modulates Calcium Mobilization. Mol Pharmacol 94:1352-1362
Singh, Kshipra; Coburn, Lori A; Asim, Mohammad et al. (2018) Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses. Cancer Res 78:4303-4315

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