Abstract

The Peptide Sequencing and Amino Acid Analysis Shared Resource provides essentially four different services that include the analyses of N-terminal amino acid sequence, internal sequence and amino acid composition and the purification of peptides. Since September 1995, when the Cancer Center Support Grant was funded, this resource has served 38 different Cancer Center investigators (of a total of 74 investigators at Vanderbilt University). Over 317 samples have been analyzed for their peptide sequences and 402 amino acid compositions have been determined within the same time period. The overall usage by the Cancer Center investigators accounts for approximately 57.4 percent of the entire usage. This Resource will continue to provide the four existing services to meet the demand for the identification of peptides and for acquiring the basic knowledge of the structural information of peptides.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA068485-06
Application #
6495360
Study Section
Subcommittee E - Prevention &Control (NCI)
Project Start
2001-09-01
Project End
2002-08-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37203

  Publications

West, Kathryn L; Kelm, Nathaniel D; Carson, Robert P et al. (2018) Myelin volume fraction imaging with MRI. Neuroimage 182:511-521
Lu, Sichang; McGough, Madison A P; Shiels, Stefanie M et al. (2018) Settable polymer/ceramic composite bone grafts stabilize weight-bearing tibial plateau slot defects and integrate with host bone in an ovine model. Biomaterials 179:29-45
Santos Guasch, Gabriela L; Beeler, J Scott; Marshall, Clayton B et al. (2018) p73 Is Required for Ovarian Follicle Development and Regulates a Gene Network Involved in Cell-to-Cell Adhesion. iScience 8:236-249
Rohrbough, Jeffrey; Nguyen, Hong-Ngan; Lamb, Fred S (2018) Modulation of ClC-3 gating and proton/anion exchange by internal and external protons and the anion selectivity filter. J Physiol 596:4091-4119
May-Zhang, Aaron A; Deal, Karen K; Southard-Smith, E Michelle (2018) Optimization of Laser-Capture Microdissection for the Isolation of Enteric Ganglia from Fresh-Frozen Human Tissue. J Vis Exp :
Zhao, Shilin; Jing, Wang; Samuels, David C et al. (2018) Strategies for processing and quality control of Illumina genotyping arrays. Brief Bioinform 19:765-775
Goff, Laura W; Azad, Nilofer S; Stein, Stacey et al. (2018) Phase I study combining the aurora kinase a inhibitor alisertib with mFOLFOX in gastrointestinal cancer. Invest New Drugs :
Payton, Rebecca R; Rispoli, Louisa A; Nagle, Kimberly A et al. (2018) Mitochondrial-related consequences of heat stress exposure during bovine oocyte maturation persist in early embryo development. J Reprod Dev 64:243-251
Kovtun, Oleg; Tomlinson, Ian D; Bailey, Danielle M et al. (2018) Single Quantum Dot Tracking Illuminates Neuroscience at the Nanoscale. Chem Phys Lett 706:741-752
Schlegel, Cameron; Lapierre, Lynne A; Weis, Victoria G et al. (2018) Reversible deficits in apical transporter trafficking associated with deficiency in diacylglycerol acyltransferase. Traffic 19:879-892

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