The Cancer Research Center of Hawaii (CRCH) is an NCI-designated Clinical Cancer Center. CRCH has diverse responsibility in cancer research, education, community outreach, and patient care. It is the only such institution in the State of Hawaii. Hawaii offers special research opportunities for cancer that are unparalleled elsewhere in the country or the world. The basis for the unique research opportunities in Hawaii are the ethnic and cultural variety of the State's population as well as its geographic location and unique environment. Research efforts at CRCH are organized into three research programs: Cancer Etiology, Prevention and Control, and Natural Products and Cancer Biology. All three research programs take particular advantage of the biodiversity offered by the multiethnic population of Hawaii for basic, population-based, and clinical studies as well as by the natural diversity of the tropical biosphere for drug discovery. All three programs have made significant scientific progress during the current CCSG funding cycle. Exciting and novel research results have been obtained and disseminated in over 800 publications in the international literature from 1999 until today. CRCH also operates the Hawaii Tumor Registry, one of 12 SEER registries in the country, the Cancer Information Service-Pacific, and a large Clinical Trials Unit which makes approximately 150 clinical trials available to Hawaii's cancer patients. Over the current cycle of CCSG support research space at CRCH approximately doubled, including approximately 50,000 square feet in a new research building to be completed by mid-2005. Furthermore, plans are underway to construct a new Cancer Center building of approximately 350,000 square feet which will not only provide expanded facilities for current research programs, but will include a modern outpatient care facility offering comprehensive cancer care services in partnership with the largest hospitals in the State. These developments will allow to build a strong clinical research activity in the future.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA071789-09
Application #
6955082
Study Section
Subcommittee G - Education (NCI)
Program Officer
Shafik, Hasnaa
Project Start
1997-07-01
Project End
2009-06-30
Budget Start
2005-08-15
Budget End
2006-06-30
Support Year
9
Fiscal Year
2005
Total Cost
$1,500,003
Indirect Cost
Name
University of Hawaii
Department
Type
Organized Research Units
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Loo, Lenora W M; Williams, Makana; Hernandez, Brenda Y (2018) The high and heterogeneous burden of breast cancer in Hawaii: A unique multiethnic U.S. Population. Cancer Epidemiol 58:71-76
Hernandez, Brenda Y; Tareg, Aileen C; Reichhardt, Martina et al. (2018) Randomized controlled trial evaluating the utility of urine HPV DNA for cervical cancer screening in a Pacific Island population. J Glob Health Rep 2:
Gu, Yuanzhuo; Wei, Xiyang; Sun, Yulin et al. (2018) miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features. Cancer Res :
Lim, Unhee; Monroe, Kristine R; Buchthal, Steve et al. (2018) Propensity for Intra-abdominal and Hepatic Adiposity Varies Among Ethnic Groups. Gastroenterology :
Maskarinec, Gertraud; Ju, Dan; Fong, Jaimie et al. (2018) Mammographic density and breast tissue expression of inflammatory markers, growth factors, and vimentin. BMC Cancer 18:1191
Amshoff, Yvette; Maskarinec, Gertraud; Shvetsov, Yurii B et al. (2018) Type 2 diabetes and colorectal cancer survival: The multiethnic cohort. Int J Cancer 143:263-268
Maskarinec, Gertraud; Jacobs, Simone; Amshoff, Yvette et al. (2018) Sleep duration and incidence of type 2 diabetes: the Multiethnic Cohort. Sleep Health 4:27-32
Conroy, Shannon M; Shariff-Marco, Salma; Yang, Juan et al. (2018) Characterizing the neighborhood obesogenic environment in the Multiethnic Cohort: a multi-level infrastructure for cancer health disparities research. Cancer Causes Control 29:167-183
Shimizu, Yoshiko; Furuya, Hideki; Tamashiro, Paulette M et al. (2018) Genetic deletion of sphingosine kinase 1 suppresses mouse breast tumor development in an HER2 transgenic model. Carcinogenesis 39:47-55
Aumueller, Nicole; Boushey, Carol J; Franke, Adrian A et al. (2018) Diet quality measured by four a priori-defined diet quality indices is associated with lipid-soluble micronutrients in the Multiethnic Cohort Study (MEC). Eur J Clin Nutr :

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