Abstract

Information about the feasibility or proof of principle of translational research interventions is supported through the CCSG Protocol-Specific Research mechanism. The Center plans to continue supporting one to three short-term pilot, or Phase I clinical trials each year. Overall Center Protocol-Specific Research activities will be supervised by the Director of the Center's Clinical Trials Unit. The Protocol Specific Research component of the CCSG has been of great importance in enabling new innovative pilot studies in cancer treatment and prevention. Funding for a research nurse has enabled us to establish and maintain research partnerships and operating procedures for working with community practitioners and medical centers. Given the nature of health care delivery to cancer patients in Hawaii, the majority of CRCH-generated studies have been in the Center's high scientific priority areas of cancer prevention and symptom control. As additional clinical research capacity develops over the next few years, we anticipate more projects testing innovative cancer treatments.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA071789-12
Application #
7680239
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
12
Fiscal Year
2008
Total Cost
$99,847
Indirect Cost

  Institution

Name
University of Hawaii
Department
Type
DUNS #
965088057
City
Honolulu
State
HI
Country
United States
Zip Code
96822

  Publications

Naderi, Ali (2018) SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies. Mol Oncol 12:724-755
Franke, Adrian A; Li, Xingnan; Menden, Ariane et al. (2018) Oxytocin analysis from human serum, urine, and saliva by orbitrap liquid chromatography-mass spectrometry. Drug Test Anal :
Fanidi, Anouar; Muller, David C; Yuan, Jian-Min et al. (2018) Circulating Folate, Vitamin B6, and Methionine in Relation to Lung Cancer Risk in the Lung Cancer Cohort Consortium (LC3). J Natl Cancer Inst 110:
Rohrmann, Sabine; Shvetsov, Yurii B; Morimoto, Yukiko et al. (2018) Self-reported dietary flavonoid intake and serum markers of inflammation: the multiethnic cohort. Cancer Causes Control 29:601-607
Faouzi, Malika; Neupane, Ram P; Yang, Jian et al. (2018) Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells. Sci Rep 8:1075
Nishioka, Scott T; Sato, Miles M; Wong, Linda L et al. (2018) Clinical and molecular sub-classification of hepatocellular carcinoma relative to alpha-fetoprotein level in an Asia-Pacific island cohort. Hepatoma Res 4:
Marciel, Michael P; Rose, Aaron H; Martinez, Verena et al. (2018) Calpain-2 inhibitor treatment preferentially reduces tumor progression for human colon cancer cells expressing highest levels of this enzyme. Cancer Med 7:175-183
Shi, Geng-Xian; Yang, Won Seok; Jin, Ling et al. (2018) RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases. Proc Natl Acad Sci U S A 115:E190-E199
Citronberg, Jessica S; Wilkens, Lynne R; Le Marchand, Loic et al. (2018) Plasma lipopolysaccharide-binding protein and colorectal cancer risk: a nested case-control study in the Multiethnic Cohort. Cancer Causes Control 29:115-123
Panizza, Chloe E; Shvetsov, Yurii B; Harmon, Brook E et al. (2018) Testing the Predictive Validity of the Healthy Eating Index-2015 in the Multiethnic Cohort: Is the Score Associated with a Reduced Risk of All-Cause and Cause-Specific Mortality? Nutrients 10:

Showing the most recent 10 out of 562 publications