Rutgers Cancer Institute of New Jersey (CINJ) is the State of New Jersey's only National Cancer Institute (NCI)-designated Comprehensive Cancer Center. The mission of CINJ is to reduce the burden of cancer by advancing cancer research, prevention, screening and education for one of the nation?s most diverse and densely populated states and therefore considers the entire State of New Jersey (NJ) its catchment area. With 21 counties, New Jersey is one of the most racially, ethnically and socioeconomically diverse regions in the US. The State is home to a large immigrant and minority population. As a whole, New Jersey is a well- educated and high-income state. However, this statistic conceals disparities in education level, English language proficiency, immigrant status, income, population density, and access to cancer care. The three major cities in the State - Newark, Trenton, and Camden - have a large population of minority, low income, and immigrant residents. The age-adjusted incidence rate of cancer in NJ is significantly higher than the US average. NJ ranked 6th in the nation in 2010-2014 in cancer incidence rates. The top five cancers in NJ mirror the top cancers in the US. Incidence of prostate, lung, colorectal, bladder, and melanoma ranked highest among men. Incidence of breast, lung, colorectal, uterine, and thyroid cancers ranked highest among women. The top five cancer sites with the highest mortality rates include lung, prostate, colorectal, and pancreas, liver for men and ovarian cancer for women. Cancer mortality in NJ is higher than the US average for colorectal cancer (men and women) and breast and pancreas cancers (women). Although overall cancer incidence in NJ has declined, there have been significant increases in breast, kidney (women), leukemia, liver, oral (men), pancreatic, and uterine cancers. Work conducted by CINJ investigators has elucidated a number of disparities in cancer incidence and mortality with regard to race/ethnicity and geographic location. This information has been used to guide research and outreach activities. CINJ conducts research and delivers outreach services that focus on cancers that pose a significant burden to the NJ population. Research and outreach services address barriers to access to cancer care and prevention services and modify health behaviors that are associated with increased cancer risk.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA072720-20
Application #
9632908
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2019-03-07
Budget End
2020-02-29
Support Year
20
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Rbhs -Cancer Institute of New Jersey
Department
Type
DUNS #
078728091
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Chan, Chang S; Laddha, Saurabh V; Lewis, Peter W et al. (2018) ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup. Nat Commun 9:4158
Panda, Anshuman; de Cubas, Aguirre A; Stein, Mark et al. (2018) Endogenous retrovirus expression is associated with response to immune checkpoint blockade in clear cell renal cell carcinoma. JCI Insight 3:
Warner, Wayne A; Lee, Tammy Y; Fang, Fang et al. (2018) The burden of prostate cancer in Trinidad and Tobago: one of the highest mortality rates in the world. Cancer Causes Control 29:685-697
Zhao, Yuhan; Wu, Lihua; Yue, Xuetian et al. (2018) A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models. Elife 7:
Deek, Matthew P; Kim, Sinae; Ahmed, Inaya et al. (2018) Prognostic Impact of Missed Chemotherapy Doses During Chemoradiation Therapy for Non-Small Cell Lung Cancer. Am J Clin Oncol 41:362-366
O'Malley, Denalee; Dewan, Asa A; Ohman-Strickland, Pamela A et al. (2018) Determinants of patient activation in a community sample of breast and prostate cancer survivors. Psychooncology 27:132-140
Park, Kihan; Chen, Wenjin; Chekmareva, Marina A et al. (2018) Electromechanical Coupling Factor of Breast Tissue as a Biomarker for Breast Cancer. IEEE Trans Biomed Eng 65:96-103
Jang, Thomas L; Patel, Neal; Faiena, Izak et al. (2018) Comparative effectiveness of radical prostatectomy with adjuvant radiotherapy versus radiotherapy plus androgen deprivation therapy for men with advanced prostate cancer. Cancer 124:4010-4022
Gupta, Apar; Ohri, Nisha; Haffty, Bruce G (2018) Hypofractionated radiation treatment in the management of breast cancer. Expert Rev Anticancer Ther 18:793-803
Patrizii, Michele; Bartucci, Monica; Pine, Sharon R et al. (2018) Utility of Glioblastoma Patient-Derived Orthotopic Xenografts in Drug Discovery and Personalized Therapy. Front Oncol 8:23

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